A new cruzipain-mediated pathway of human cell invasion by Trypanosoma cruzi requires trypomastigote membranes
about
A cysteine protease inhibitor cures Chagas' disease in an immunodeficient-mouse model of infectionIn Vitro and In Vivo Studies of the Trypanocidal Properties of WRR-483 against Trypanosoma cruziMechanisms of Infectivity and Evasion Derived from Microvesicles Cargo Produced by Trypanosoma cruziSpecific Endocytosis Blockade of Trypanosoma cruzi Exposed to a Poly-LAcNAc Binding Lectin Suggests that Lectin-Sugar Interactions Participate to Receptor-Mediated EndocytosisA cysteine protease inhibitor of plasmodium berghei is essential for exo-erythrocytic developmentCruzipain promotes Trypanosoma cruzi adhesion to Rhodnius prolixus midgutBlood-brain barrier traversal by African trypanosomes requires calcium signaling induced by parasite cysteine protease.mRNA localization mechanisms in Trypanosoma cruziMolecular characterization of Trypanosoma cruzi SAP proteins with host-cell lysosome exocytosis-inducing activity required for parasite invasionMolecular basis of mammalian cell invasion by Trypanosoma cruzi.Molecular and biochemical characterization of a cathepsin B-like protease family unique to Trypanosoma congolenseAngiotensin-converting enzyme limits inflammation elicited by Trypanosoma cruzi cysteine proteases: a peripheral mechanism regulating adaptive immunity via the innate kinin pathway.Reversible cysteine protease inhibitors show promise for a Chagas disease cure.Looking at the proteases from a simple perspective.Use of cysteine-reactive small molecules in drug discovery for trypanosomal disease.Knockout of the gamma subunit of the AP-1 adaptor complex in the human parasite Trypanosoma cruzi impairs infectivity and differentiation and prevents the maturation and targeting of the major protease cruzipain.Novel scaffolds for inhibition of Cruzipain identified from high-throughput screening of anti-kinetoplastid chemical boxes.Phospholipases a in trypanosomatids.The kallikrein-kinin system in experimental Chagas disease: a paradigm to investigate the impact of inflammatory edema on GPCR-mediated pathways of host cell invasion by Trypanosoma cruzi.Optimization of peptidyl allyl sulfones as clan CA cysteine protease inhibitors.Extracellular vesicles shed by Trypanosoma cruzi are linked to small RNA pathways, life cycle regulation, and susceptibility to infection of mammalian cells.Protease expression analysis in recently field-isolated strains of Trypanosoma cruzi: a heterogeneous profile of cysteine protease activities between TC I and TC II major phylogenetic groups.Novel cysteine proteinase in Trypanosoma cruzi metacyclogenesis.Application of bioisosterism in design of the semicarbazone derivatives as cruzain inhibitors: a theoretical and experimental study.Proteomic analysis reveals different composition of extracellular vesicles released by two Trypanosoma cruzi strains associated with their distinct interaction with host cells.
P2860
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P2860
A new cruzipain-mediated pathway of human cell invasion by Trypanosoma cruzi requires trypomastigote membranes
description
2004 nî lūn-bûn
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2004年の論文
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name
A new cruzipain-mediated pathw ...... uires trypomastigote membranes
@en
type
label
A new cruzipain-mediated pathw ...... uires trypomastigote membranes
@en
prefLabel
A new cruzipain-mediated pathw ...... uires trypomastigote membranes
@en
P2093
P2860
P1476
A new cruzipain-mediated pathw ...... uires trypomastigote membranes
@en
P2093
Ana Paula C A Lima
Isabela M Aparicio
Julio Scharfstein
P2860
P304
P356
10.1128/IAI.72.10.5892-5902.2004
P407
P577
2004-10-01T00:00:00Z