Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling.
about
Oligomerization of ETO is obligatory for corepressor interactionGenomic sequence, structural organization, molecular evolution, and aberrant rearrangement of promyelocytic leukemia zinc finger geneThe serine-threonine kinase MNK1 is post-translationally stabilized by PML-RARalpha and regulates differentiation of hematopoietic cellsPIC-1/SUMO-1-modified PML-retinoic acid receptor alpha mediates arsenic trioxide-induced apoptosis in acute promyelocytic leukemiaDNA recognition by the aberrant retinoic acid receptors implicated in human acute promyelocytic leukemiaComprehensive genomic screens identify a role for PLZF-RARalpha as a positive regulator of cell proliferation via direct regulation of c-MYCProlonged intracellular accumulation of light-inducible nanoparticles in leukemia cells allows their remote activationAcute promyelocytic leukemia: from treatment to genetics and back.CCAAT/enhancer binding protein epsilon is a potential retinoid target gene in acute promyelocytic leukemia treatment.Characterisation of genome-wide PLZF/RARA target genes.Retinoic acid receptor alpha (RAralpha) Mutations in Human Leukemia.Common themes in the pathogenesis of acute myeloid leukemia.In vivo analysis of the molecular genetics of acute promyelocytic leukemia.Translocations of the RARalpha gene in acute promyelocytic leukemia.Transcriptional regulation in acute promyelocytic leukemia.The theory of APL.Retinoid target genes in acute promyelocytic leukemia.Acute promyelocytic leukemia: PML/RARalpha and the leukemic stem cell.The promyelocytic leukemia zinc finger protein: two decades of molecular oncologyIn vivo analysis of the role of aberrant histone deacetylase recruitment and RAR alpha blockade in the pathogenesis of acute promyelocytic leukemia.8-CPT-cAMP/all-trans retinoic acid targets t(11;17) acute promyelocytic leukemia through enhanced cell differentiation and PLZF/RARα degradation.Cross-talk between retinoic acid and interferons: molecular mechanisms of interaction in acute promyelocytic leukemia cells.The PRC1 Polycomb group complex interacts with PLZF/RARA to mediate leukemic transformationRole of autophagy in acute myeloid leukemia therapy.RARA fusion genes in acute promyelocytic leukemia: a review.Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.Acute myeloid leukemia fusion proteins deregulate genes involved in stem cell maintenance and DNA repairRegulation of hematopoietic development by ZBTB transcription factors.NPM-RAR, not the RAR-NPM reciprocal t(5;17)(q35;q21) acute promyelocytic leukemia fusion protein, inhibits myeloid differentiation.The promyelocytic leukemia zinc finger protein affects myeloid cell growth, differentiation, and apoptosis.Response of retinoic acid-resistant KG1 cells to combination of retinoic acid with diverse histone deacetylase inhibitors.Promyelocytic leukemia-nuclear body formation is an early event leading to retinoic acid-induced differentiation of neuroblastoma cells.C/EBPbeta: a major PML-RARA-responsive gene in retinoic acid-induced differentiation of APL cells.Co-operative DNA binding by GAGA transcription factor requires the conserved BTB/POZ domain and reorganizes promoter topologySynthetic retinoids dissociate coactivator binding from corepressor release.Fusion proteins of retinoid receptors antagonize TGF-beta-induced growth inhibition of lung epithelial cells.Leukemia-associated translocation products able to activate RAS modify PML and render cells sensitive to arsenic-induced apoptosis.Formation of PML/RAR alpha high molecular weight nuclear complexes through the PML coiled-coil region is essential for the PML/RAR alpha-mediated retinoic acid response.A function of p21 during promyelocytic leukemia cell differentiation independent of CDK inhibition and cell cycle arrest.Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL.
P2860
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P2860
Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Opposite effects of the acute ...... s on retinoic acid signalling.
@en
type
label
Opposite effects of the acute ...... s on retinoic acid signalling.
@en
prefLabel
Opposite effects of the acute ...... s on retinoic acid signalling.
@en
P2093
P2860
P50
P356
P1476
Opposite effects of the acute ...... ns on retinoic acid signalling
@en
P2093
P2860
P304
P356
10.1128/MCB.17.8.4859
P407
P577
1997-08-01T00:00:00Z