Overexpression of EPHA2 receptor destabilizes adherens junctions via a RhoA-dependent mechanism.
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Ligand targeting of EphA2 enhances keratinocyte adhesion and differentiation via desmoglein 1The role of Eph receptors in lens function and diseaseDesign and evaluation of EphrinA1 mutants with cerebral protective effect.Major role of epidermal growth factor receptor and Src kinases in promoting oxidative stress-dependent loss of adhesion and apoptosis in epithelial cells.High EphA2 protein expression in renal cell carcinoma is associated with a poor disease outcome.Eph receptors and ephrins in cancer: bidirectional signalling and beyond.Transactivation of the receptor-tyrosine kinase ephrin receptor A2 is required for the low molecular weight hyaluronan-mediated angiogenesis that is implicated in tumor progression.Roles of the cytoskeleton in regulating EphA2 signals.Matrix metalloproteinases and protein tyrosine kinases: potential novel targets in acute lung injury and ARDSSoluble ephrin a1 is necessary for the growth of HeLa and SK-BR3 cellsLow molecular weight protein tyrosine phosphatase isoforms regulate breast cancer cells migration through a RhoA dependent mechanism.In PC3 prostate cancer cells ephrin receptors crosstalk to β1-integrins to strengthen adhesion to collagen type I.Hsp90 is an essential regulator of EphA2 receptor stability and signaling: implications for cancer cell migration and metastasis.EphB2 activation is required for ependymoma development as well as inhibits differentiation and promotes proliferation of the transformed cell.Eph-A2 promotes permeability and inflammatory responses to bleomycin-induced lung injury.The receptor tyrosine kinase EphA2 is a direct target gene of hypermethylated in cancer 1 (HIC1).Advances in malignant pleural mesothelioma therapy: targeting EphA2 a novel approach.EphA2 activation promotes the endothelial cell inflammatory response: a potential role in atherosclerosisCross-talk between the Tissue Factor/coagulation factor VIIa complex and the tyrosine kinase receptor EphA2 in cancerEph/ephrin signaling in epidermal differentiation and diseaseRegulation of adherens junction dynamics by phosphorylation switches.Eph receptor and ephrin function in breast, gut, and skin epithelia.Proteomic analysis of acquired tamoxifen resistance in MCF-7 cells reveals expression signatures associated with enhanced migration.EphA2 Receptor Unliganded Dimers Suppress EphA2 Pro-tumorigenic Signaling.Ligand-independent activation of EphA2 by arachidonic acid induces metastasis-like behaviour in prostate cancer cells.The status of intercellular junctions in established lens epithelial cell lines.EPHA2 MUTATIONS CONTRIBUTE TO CONGENITAL CATARACT THROUGH DIVERSE MECHANISMSFurther analysis of the lens of ephrin-A5-/- mice: development of postnatal defectsIdentification and functional analysis of phosphorylated tyrosine residues within EphA2 receptor tyrosine kinase.Regulation of tumor initiation and metastatic progression by Eph receptor tyrosine kinases.Endothelial EphA receptor stimulation increases lung vascular permeability.Whole-transcriptome analysis of UUO mouse model of renal fibrosis reveals new molecular players in kidney diseasesInduction of cell retraction by the combined actions of Abl-CrkII and Rho-ROCK1 signaling.Eph receptors in breast cancer: roles in tumor promotion and tumor suppression.EphA2 overexpression promotes ovarian cancer growth.Tumoristatic effects of endostatin in prostate cancer is dependent on androgen receptor status.PKCdelta influences p190 phosphorylation and activity: events independent of PKCdelta-mediated regulation of endothelial cell stress fiber and focal adhesion formation and barrier function.EphA2 receptor mediates increased vascular permeability in lung injury due to viral infection and hypoxia.Emerging roles of Semaphorins in the regulation of epithelial and endothelial junctionsRoles of EphA2 in Development and Disease.
P2860
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P2860
Overexpression of EPHA2 receptor destabilizes adherens junctions via a RhoA-dependent mechanism.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Overexpression of EPHA2 recept ...... ia a RhoA-dependent mechanism.
@en
type
label
Overexpression of EPHA2 recept ...... ia a RhoA-dependent mechanism.
@en
prefLabel
Overexpression of EPHA2 recept ...... ia a RhoA-dependent mechanism.
@en
P2093
P50
P356
P1476
Overexpression of EPHA2 recept ...... via a RhoA-dependent mechanism
@en
P2093
Al Reynolds
Reneé C Ireton
Wei Bin Fang
P304
P356
10.1242/JCS.017145
P407
P577
2008-01-15T00:00:00Z