Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells.
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DNA methylation in stem cell renewal and multipotencyTargeting of de novo DNA methylation throughout the Oct-4 gene regulatory region in differentiating embryonic stem cellsTranscriptional repression and DNA hypermethylation of a small set of ES cell marker genes in male germline stem cellsReduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysisOverexpression of hTERT increases stem-like properties and decreases spontaneous differentiation in human mesenchymal stem cell linesEmbryonic stem cell and induced pluripotent stem cell: an epigenetic perspectiveLong noncoding RNAs in DNA methylation: new players stepping into the old gameCommon stemness regulators of embryonic and cancer stem cellsEx uno plures: molecular designs for embryonic pluripotencyChromatin structure of pluripotent stem cells and induced pluripotent stem cells.Epigenetic regulation of the intestinal epitheliumEpigenetic mechanisms of neurodegeneration in Huntington's diseaseRole of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specificationTet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cellsThe NuRD component Mbd3 is required for pluripotency of embryonic stem cellsDicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencingEpigenetic regulation in the inner ear and its potential roles in development, protection, and regeneration.A model for genetic and epigenetic regulatory networks identifies rare pathways for transcription factor induced pluripotency.A combined epigenetic and non-genetic approach for reprogramming human somatic cellsEpigenome remodelling in breast cancer: insights from an early in vitro model of carcinogenesisThe placenta: transcriptional, epigenetic, and physiological integration during developmentFine-tuning of epigenetic regulation with respect to promoter CpG content in a cell type-specific manner.Decitabine suspends human CD34+ cell differentiation and proliferation during lentiviral transduction.Genomic distribution and inter-sample variation of non-CpG methylation across human cell types.Epigenetic modifications in pluripotent and differentiated cells.Epigenetic regulation of open chromatin in pluripotent stem cells.Epigenetic changes in Alzheimer's disease: decrements in DNA methylationCpG methylation of half-CRE sequences creates C/EBPalpha binding sites that activate some tissue-specific genes.LSH and G9a/GLP complex are required for developmentally programmed DNA methylation.Global DNA hypomethylation prevents consolidation of differentiation programs and allows reversion to the embryonic stem cell state.A sensitive mass spectrometry method for simultaneous quantification of DNA methylation and hydroxymethylation levels in biological samplesCell cycle-dependent turnover of 5-hydroxymethyl cytosine in mouse embryonic stem cells.Temporal uncoupling of the DNA methylome and transcriptional repression during embryogenesisDNA methylation dynamics in muscle development and disease.Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells.GADD45A protein plays an essential role in active DNA demethylation during terminal osteogenic differentiation of adipose-derived mesenchymal stem cellsCoordinated epigenetic remodelling of transcriptional networks occurs during early breast carcinogenesis.Overlapping DNA methylation dynamics in mouse intestinal cell differentiation and early stages of malignant progressionTET family proteins and their role in stem cell differentiation and transformation.AUF1 cell cycle variations define genomic DNA methylation by regulation of DNMT1 mRNA stability
P2860
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P2860
Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Severe global DNA hypomethylat ...... ation in embryonic stem cells.
@en
type
label
Severe global DNA hypomethylat ...... ation in embryonic stem cells.
@en
prefLabel
Severe global DNA hypomethylat ...... ation in embryonic stem cells.
@en
P2093
P2860
P1476
Severe global DNA hypomethylat ...... lation in embryonic stem cells
@en
P2093
Anna Krassowska
Bernard Ramsahoye
John Ansell
Lesley Forrester
Melany Jackson
Timothy Chevassut
P2860
P304
P356
10.1128/MCB.24.20.8862-8871.2004
P407
P50
P577
2004-10-01T00:00:00Z