Inverse agonist and neutral antagonist actions of antidepressants at recombinant and native 5-hydroxytryptamine2C receptors: differential modulation of cell surface expression and signal transduction.
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SB 206553, a putative 5-HT2C inverse agonist, attenuates methamphetamine-seeking in ratsMirtazapine, and mirtazapine-like compounds as possible pharmacotherapy for substance abuse disorders: evidence from the bench and the bedsideRecovery of neuronal and network excitability after spinal cord injury and implications for spasticityNucleus accumbens shell excitability is decreased by methamphetamine self-administration and increased by 5-HT2C receptor inverse agonism and agonism.Pharmacotherapeutic agents in the treatment of methamphetamine dependence.Recovery of motoneuron and locomotor function after spinal cord injury depends on constitutive activity in 5-HT2C receptors.Quantitative phosphoproteomics unravels biased phosphorylation of serotonin 2A receptor at Ser280 by hallucinogenic versus nonhallucinogenic agonists.Serotonin 2c receptor RNA editing in major depression and suicide.The efficacy of mirtazapine in the treatment of cocaine dependence with comorbid depression.5-hydroxtryptamine receptors in systemic hypertension: an arterial focus.Quantitative changes in intracellular calcium and extracellular-regulated kinase activation measured in parallel in CHO cells stably expressing serotonin (5-HT) 5-HT2A or 5-HT2C receptors.Locomotion after spinal cord injury depends on constitutive activity in serotonin receptorsMirtazapine alters cue-associated methamphetamine seeking in ratsMotoneuron excitability and muscle spasms are regulated by 5-HT2B and 5-HT2C receptor activity.Prevention of 5-hydroxytryptamine2C receptor RNA editing and alternate splicing in C57BL/6 mice activates the hypothalamic-pituitary-adrenal axis and alters moodFine-tuning serotonin2c receptor function in the brain: molecular and functional implicationsG Protein-coupled Receptor Kinases of the GRK4 Protein Subfamily Phosphorylate Inactive G Protein-coupled Receptors (GPCRs).The atypical antidepressant mirtazapine attenuates expression of morphine-induced place preference and motor sensitization.Physical interaction of calmodulin with the 5-hydroxytryptamine2C receptor C-terminus is essential for G protein-independent, arrestin-dependent receptor signaling.The implications of gene-environment interactions in depression: will cause inform cure?Phosphorylation of β-arrestin2 at Thr383 by MEK underlies β-arrestin-dependent activation of Erk1/2 by GPCRs.Trazodone: properties and utility in multiple disorders.Type-1 cannabinoid receptor signaling in neuronal development.5-HT2 receptors-mediated modulation of voltage-gated K+ channels and neurophysiopathological correlates.The vital role of constitutive GPCR activity in the mesolimbic dopamine system.Agomelatine: mechanism of action and pharmacological profile in relation to antidepressant properties.Serotonergic transmission after spinal cord injury.New insights on the antidepressant discontinuation syndrome.Mirtazapine and ketanserin alter preference for gambling-like schedules of reinforcement in rats.Suppression of metastasis by mirtazapine via restoration of the Lin-7C/β-catenin pathway in human cancer cellsConstitutive Desensitization of Opioid Receptors in Peripheral Sensory Neurons.Activation-dependent plasticity of polarized GPCR distribution on the neuronal surface.RNA editing of the serotonin 2C receptor and expression of Galpha(q) protein: genetic mouse models do not support a role for regulation or compensation.Unusual weight fluctuation under corticosteroid and psychotropic treatment.Comparative Evaluation of Partial α2 -Adrenoceptor Agonist and Pure α2 -Adrenoceptor Antagonist on the Behavioural Symptoms of Withdrawal after Chronic Alcohol Administration in Mice.Chronic escitalopram treatment caused dissociative adaptation in serotonin (5-HT) 2C receptor antagonist-induced effects in REM sleep, wake and theta wave activity.Structure-Based Scaffold Repurposing for G Protein-Coupled Receptors: Transformation of Adenosine Derivatives into 5HT2B/5HT2C Serotonin Receptor Antagonists.Emergence of Serotonergic Neurons After Spinal Cord Injury in Turtles.
P2860
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P2860
Inverse agonist and neutral antagonist actions of antidepressants at recombinant and native 5-hydroxytryptamine2C receptors: differential modulation of cell surface expression and signal transduction.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Inverse agonist and neutral an ...... ssion and signal transduction.
@en
type
label
Inverse agonist and neutral an ...... ssion and signal transduction.
@en
prefLabel
Inverse agonist and neutral an ...... ssion and signal transduction.
@en
P2093
P356
P1476
Inverse agonist and neutral an ...... ssion and signal transduction.
@en
P2093
Benjamin Chanrion
Clotilde Mannoury la Cour
Jean-François Pujol
Joël Bockaert
Laurent Vincent
Mark J Millan
Mathieu Seimandi
Philippe Marin
Sophie Gavarini
P304
P356
10.1124/MOL.107.041574
P577
2007-12-14T00:00:00Z