Immune modulation by melanoma and ovarian tumor cells through expression of the immunosuppressive molecule CD200.
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The immunosuppressive surface ligand CD200 augments the metastatic capacity of squamous cell carcinoma.Melanoma cell expression of CD200 inhibits tumor formation and lung metastasis via inhibition of myeloid cell functions.Tumor expression of CD200 inhibits IL-10 production by tumor-associated myeloid cells and prevents tumor immune evasion of CTL therapy.Comparison of immunity in mice cured of primary/metastatic growth of EMT6 or 4THM breast cancer by chemotherapy or immunotherapyCD200 expression suppresses natural killer cell function and directly inhibits patient anti-tumor response in acute myeloid leukemiaThe classification of microglial activation phenotypes on neurodegeneration and regeneration in Alzheimer's disease brain.Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: establishing a reversible immune evasion mechanism in human cancer.Over-Expression of CD200 Predicts Poor Prognosis in Cutaneous Squamous Cell CarcinomaPI(3) kinase is associated with a mechanism of immunoresistance in breast and prostate cancerCure of metastatic growth of EMT6 tumor cells in mice following manipulation of CD200:CD200R signaling.Decreased expression of CD200 and CD200 receptor in Alzheimer's disease: a potential mechanism leading to chronic inflammation.Cancer and pregnancy: parallels in growth, invasion, and immune modulation and implications for cancer therapeutic agents.Antibodies targeting cancer stem cells: a new paradigm in immunotherapy?Combination of targeted therapy and immunotherapy in melanoma.Programmed cell removal: a new obstacle in the road to developing cancer.Treatment failure in patients with HPV 16-induced vulvar intraepithelial neoplasia: understanding different clinical responses to immunotherapy.Combination immunotherapy approaches.A comparison of serum miRNAs influencing metastatic growth of EMT6 vs 4THM tumor cells in wild-type and CD200R1KO mice.Long term potentiation is impaired in membrane glycoprotein CD200-deficient mice: a role for Toll-like receptor activation.Negative immune checkpoints on T lymphocytes and their relevance to cancer immunotherapy.A Truncated form of CD200 (CD200S) Expressed on Glioma Cells Prolonged Survival in a Rat Glioma Model by Induction of a Dendritic Cell-Like Phenotype in Tumor-Associated Macrophages.Checkpoint Proteins in Pediatric Brain and Extracranial Solid Tumors: Opportunities for Immunotherapy.Targeting of heme oxygenase-1 as a novel immune regulator of neuroblastoma.Flow cytometric analysis of CD200 expression by pulmonary small cell carcinoma.Tumor-derived vaccines containing CD200 inhibit immune activation: implications for immunotherapy.Role of CD200 expression in regulation of metastasis of EMT6 tumor cells in mice.Expression of CD200 on AML blasts directly suppresses memory T-cell function.CD200 expression in plasma cells of nonmyeloma immunoproliferative disorders: clinicopathologic features and comparison with plasma cell myeloma.Upregulation of CD200 is associated with Foxp3+ regulatory T cell expansion and disease progression in acute myeloid leukemia.Checkpoint blockade in solid tumors and B-cell malignancies, with special consideration of the role of CD200.A CD200R-CD28 fusion protein appropriates an inhibitory signal to enhance T-cell function and therapy of murine leukemia.Characteristics of Multipotent Mesenchymal Stromal Cells Isolated from Human Endometrium and Endometriosis Lesions.CD200 Expression in Neuroendocrine Neoplasms.The Receptor for the CD200 Tolerance-Signaling Molecule Associated with Successful Pregnancy is Expressed by Early-Stage Breast Cancer Cells in 80% of Patients and by Term Placental Trophoblasts.CD200-CD200R signaling suppresses anti-tumor responses independently of CD200 expression on the tumorCD200:CD200R-Mediated Regulation of Immunity
P2860
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P2860
Immune modulation by melanoma and ovarian tumor cells through expression of the immunosuppressive molecule CD200.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Immune modulation by melanoma ...... unosuppressive molecule CD200.
@en
type
label
Immune modulation by melanoma ...... unosuppressive molecule CD200.
@en
prefLabel
Immune modulation by melanoma ...... unosuppressive molecule CD200.
@en
P2093
P2860
P1476
Immune modulation by melanoma ...... unosuppressive molecule CD200.
@en
P2093
P2860
P2888
P304
P356
10.1007/S00262-007-0429-6
P577
2008-07-01T00:00:00Z
P6179
1030497926