Hypoxia-selective 3-alkyl 1,2,4-benzotriazine 1,4-dioxides: the influence of hydrogen bond donors on extravascular transport and antitumor activity.

Hypoxia-selective 3-alkyl 1,2,4-benzotriazine 1,4-dioxides: the influence of hydrogen bond donors on extravascular transport and antitumor activity.

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http://www.wikidata.org/entity/Q40041887
Redox-directed cancer therapeutics: molecular mechanisms and opportunitiesTricyclic [1,2,4]triazine 1,4-dioxides as hypoxia selective cytotoxinsInitiation of DNA strand cleavage by 1,2,4-benzotriazine 1,4-dioxide antitumor agents: mechanistic insight from studies of 3-methyl-1,2,4-benzotriazine 1,4-dioxideStructural determination of NSC 670224, synthesis of analogues and biological evaluation.Synthesis, Crystal Structure, and Rotational Energy Profile of 3-Cyclopropyl-1,2,4-benzotriazine 1,4-Di-N-oxide.DNA strand cleaving properties and hypoxia-selective cytotoxicity of 7-chloro-2-thienylcarbonyl-3-trifluoromethylquinoxaline 1,4-dioxide.Pharmacokinetic/pharmacodynamic modeling identifies SN30000 and SN29751 as tirapazamine analogues with improved tissue penetration and hypoxic cell killing in tumorsEO9 (Apaziquone): from the clinic to the laboratory and back againPhase II study of tirapazamine, cisplatin, and etoposide and concurrent thoracic radiotherapy for limited-stage small-cell lung cancer: SWOG 0222.Hypoxia-activated prodrugs in cancer therapy: progress to the clinic.Design of optimized hypoxia-activated prodrugs using pharmacokinetic/pharmacodynamic modeling.Application of Suzuki-Miyaura and Buchwald-Hartwig Cross-coupling Reactions to the Preparation of Substituted 1,2,4-Benzotriazine 1-Oxides Related to the Antitumor Agent Tirapazamine.Evaluation of different PAMAM dendrimers as molecular vehicle of 1,2,4-triazine N-oxide derivative with potential antitumor activity
P2860

Hypoxia-selective 3-alkyl 1,2,4-benzotriazine 1,4-dioxides: the influence of hydrogen bond donors on extravascular transport and antitumor activity.

Item
http://www.wikidata.org/entity/Q40041887
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Hypoxia-selective 3-alkyl 1,2, ...... nsport and antitumor activity.
@en
type
label
Hypoxia-selective 3-alkyl 1,2, ...... nsport and antitumor activity.
@en
prefLabel
Hypoxia-selective 3-alkyl 1,2, ...... nsport and antitumor activity.
@en
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
Hypoxia-selective 3-alkyl 1,2, ...... nsport and antitumor activity.
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698