about
Band 3 mutations, renal tubular acidosis and South-East Asian ovalocytosis in Malaysia and Papua New Guinea: loss of up to 95% band 3 transport in red cellsPolar residues in the second transmembrane domain of the rat P2X2 receptor that affect spontaneous gating, unitary conductance, and rectificationAltered hippocampal synaptic potentiation in P2X4 knock-out miceRole of the domain encompassing Arg304-Ile328 in rat P2X2 receptor conformation revealed by alterations in complex glycosylation at Asn298P2X receptors: dawn of the post-structure era.Expression, purification, electron microscopy, N-glycosylation mutagenesis and molecular modeling of human P2X4 and Dictyostelium discoideum P2XA.Distinct regions of human glycophorin A enhance human red cell anion exchanger (band 3; AE1) transport function and surface trafficking.Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity.Purinergic P2X receptors: structural and functional features depicted by X-ray and molecular modelling studies.Agonist binding evokes extensive conformational changes in the extracellular domain of the ATP-gated human P2X1 receptor ion channel.Red-cell glycophorin A-band 3 interactions associated with the movement of band 3 to the cell surface.Molecular shape, architecture, and size of P2X4 receptors determined using fluorescence resonance energy transfer and electron microscopyThr339-to-serine substitution in rat P2X2 receptor second transmembrane domain causes constitutive opening and indicates a gating role for Lys308.An intracellular P2X receptor required for osmoregulation in Dictyostelium discoideum.Caveolin-1 influences P2X7 receptor expression and localization in mouse lung alveolar epithelial cells.Characterization of ATP-gated P2X7 receptors in fish provides new insights into the mechanism of release of the leaderless cytokine interleukin-1 beta.Pseudoapoptosis induced by brief activation of ATP-gated P2X7 receptors.Identification of Thr283 as a key determinant of P2X7 receptor function.The Vip3Ag4 Insecticidal Protoxin from Bacillus thuringiensis Adopts A Tetrameric Configuration That Is Maintained on ProteolysisExploiting powder X-ray diffraction for direct structure determination in structural biology: the P2X4 receptor trafficking motif YEQGL.Tyrosine phosphorylation of HSP90 within the P2X7 receptor complex negatively regulates P2X7 receptors.A conductive pathway generated from fragments of the human red cell anion exchanger AE1.The N-terminal region of the transmembrane domain of human erythrocyte band 3. Residues critical for membrane insertion and transport activity.The Molecular Determinants of Small-Molecule Ligand Binding at P2X Receptors.Protein-4.2 association with band 3 (AE1, SLCA4) in Xenopus oocytes: effects of three natural protein-4.2 mutations associated with hemolytic anemia.Amino Acid Residues in the P2X7 Receptor that Mediate Differential Sensitivity to ATP and BzATPReanalysis of P2X7 receptor expression in rodent brainStudying Purinoceptor Cell-Surface Expression by Protein BiotinylationA new antiviral scaffold for human norovirus identified with computer-aided approaches on the viral polymerase
P50
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P50
description
researcher ORCID: 0000-0002-9615-9002
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wetenschapper
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Mark T. Young
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Mark T. Young
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Mark T. Young
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Mark T. Young
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Mark T. Young
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type
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Mark T. Young
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Mark T. Young
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Mark T. Young
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Mark T. Young
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Mark T. Young
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prefLabel
Mark T. Young
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Mark T. Young
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Mark T. Young
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Mark T. Young
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Mark T. Young
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P106
P1153
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0000-0002-9615-9002