Differences in antitumor effects of various statins on human pancreatic cancer.
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Simvastatin impairs growth hormone-activated signal transducer and activator of transcription (STAT) signaling pathway in UMR-106 osteosarcoma cellsStatins and pancreatic cancer.NCI60 cancer cell line panel data and RNAi analysis help identify EAF2 as a modulator of simvastatin and lovastatin response in HCT-116 cells.Statin use and risk of pancreatic cancer: a meta-analysis.Statin use and risk of pancreatic cancer: results from a large, clinic-based case-control study.Heme oxygenase is not involved in the anti-proliferative effects of statins on pancreatic cancer cells.Atorvastatin delays progression of pancreatic lesions to carcinoma by regulating PI3/AKT signaling in p48Cre/+ LSL-KrasG12D/+ mice.Different effects of statins on induction of diabetes mellitus: an experimental study.Variability in statin-induced changes in gene expression profiles of pancreatic cancer.Involvement of inflammatory factors in pancreatic carcinogenesis and preventive effects of anti-inflammatory agents.New strategies for the treatment of ovarian cancer.Exploitation of pleiotropic actions of statins by using tumour-targeted delivery systems.Differential and Joint Effects of Metformin and Statins on Overall Survival of Elderly Patients with Pancreatic Adenocarcinoma: A Large Population-Based Study.In vitro and in vivo anticancer effects of mevalonate pathway modulation on human cancer cells.The effect of simvastatin on lipid droplets accumulation in human embryonic kidney cells and pancreatic cancer cells.The differential effects of statins on the risk of developing pancreatic cancer: a case-control study in two centres in the United Kingdom.Toxicity of Atorvastatin on Pancreas Mitochondria: A Justification for Increased Risk of Diabetes Mellitus.Simvastatin stimulates apoptosis in cholangiocarcinoma by inhibition of Rac1 activity.Marketed drugs used for the management of hypercholesterolemia as anticancer armament.A screen for inducers of bHLH activity identifies pitavastatin as a regulator of p21, Rb phosphorylation and E2F target gene expression in pancreatic cancer.Statins are active in acute lymphoblastic leukaemia (ALL): a therapy that may treat ALL and prevent avascular necrosis.Medically managed hypercholesterolemia and insulin-dependent diabetes mellitus preoperatively predicts poor survival after surgery for pancreatic cancer.Randomized double-blinded, placebo-controlled phase II trial of simvastatin and gemcitabine in advanced pancreatic cancer patients.Statin use is associated with improved survival in ovarian cancer: A retrospective population-based study.Isoprenoids responsible for protein prenylation modulate the biological effects of statins on pancreatic cancer cells.Biomarker identification for statin sensitivity of cancer cell lines.The administration of drugs inhibiting cholesterol/oxysterol synthesis is safe and increases the efficacy of immunotherapeutic regimens in tumor-bearing mice.Impact of post-diagnostic statin use on ovarian cancer mortality: a systematic review and meta-analysis of observational studies.The sensitivity of head and neck carcinoma cells to statins is related to the expression of their Ras expression status, and statin-induced apoptosis is mediated via suppression of the Ras/ERK and Ras/mTOR pathways.Lipophilic statins limit cancer cell growth and survival, via involvement of Akt signaling.
P2860
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P2860
Differences in antitumor effects of various statins on human pancreatic cancer.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Differences in antitumor effects of various statins on human pancreatic cancer.
@en
type
label
Differences in antitumor effects of various statins on human pancreatic cancer.
@en
prefLabel
Differences in antitumor effects of various statins on human pancreatic cancer.
@en
P2093
P2860
P50
P356
P1476
Differences in antitumor effects of various statins on human pancreatic cancer
@en
P2093
Gabriela Dvoráková
Helena Gbelcová
Marie Zadinová
Michal Kudla
Peter Balaz
Zdenek Knejzlík
P2860
P304
P356
10.1002/IJC.23242
P577
2008-03-01T00:00:00Z