Inhibition of AMP-activated protein kinase protects pancreatic beta-cells from cytokine-mediated apoptosis and CD8+ T-cell-induced cytotoxicity.
about
AMP-activated protein kinase and pancreatic/duodenal homeobox-1 involved in insulin secretion under high leucine exposure in rat insulinoma beta-cellsAMP-activated protein kinase (AMPK) mediates nutrient regulation of thioredoxin-interacting protein (TXNIP) in pancreatic beta-cellsEvolution of β-Cell Replacement Therapy in Diabetes Mellitus: Islet Cell TransplantationAblation of AMP-activated protein kinase alpha1 and alpha2 from mouse pancreatic beta cells and RIP2.Cre neurons suppresses insulin release in vivo.AMP-activated protein kinase attenuates nitric oxide-induced beta-cell deathTranslationally controlled tumour protein (TCTP) is a novel glucose-regulated protein that is important for survival of pancreatic beta cells.LKB1 deletion with the RIP2.Cre transgene modifies pancreatic beta-cell morphology and enhances insulin secretion in vivo.Targeted therapies of the LKB1/AMPK pathway for the treatment of insulin resistanceAMP-activated protein kinase mediates apoptosis in response to bioenergetic stress through activation of the pro-apoptotic Bcl-2 homology domain-3-only protein BMFAMP-activated protein kinase (AMPK) negatively regulates Nox4-dependent activation of p53 and epithelial cell apoptosis in diabetes.miR-296-3p, miR-298-5p and their downstream networks are causally involved in the higher resistance of mammalian pancreatic α cells to cytokine-induced apoptosis as compared to β cellsRegulation of Pancreatic β Cell Mass by Cross-Interaction between CCAAT Enhancer Binding Protein β Induced by Endoplasmic Reticulum Stress and AMP-Activated Protein Kinase Activity.Nitric oxide stress and activation of AMP-activated protein kinase impair β-cell sarcoendoplasmic reticulum calcium ATPase 2b activity and protein stabilityGlucagon-like peptide-1 prevents methylglyoxal-induced apoptosis of beta cells through improving mitochondrial function and suppressing prolonged AMPK activation.Sorcin Links Pancreatic β-Cell Lipotoxicity to ER Ca2+ Stores.Targeting the AMPK pathway for the treatment of Type 2 diabetes.AMP-activated protein kinase mediates the interferon-gamma-induced decrease in intestinal epithelial barrier function.Roles of mitochondria in human disease.AMP-activated protein kinase and metabolic control.AMP-activated protein kinase modulators: a patent review (2006 - 2010).Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation.Acute and long-term effects of metformin on the function and insulin secretory responsiveness of clonal β-cells.Connexin36 contributes to INS-1E cells survival through modulation of cytokine-induced oxidative stress, ER stress and AMPK activity.Activation of autophagy through modulation of 5'-AMP-activated protein kinase protects pancreatic beta-cells from high glucose.Candidate gene identification of ovulation-inducing genes by RNA sequencing with an in vivo assay in zebrafish.Roles of hyperuricemia in metabolic syndrome and cardiac-kidney-vascular system diseasesThe Impact of Pancreatic Beta Cell Heterogeneity on Type 1 Diabetes Pathogenesis
P2860
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P2860
Inhibition of AMP-activated protein kinase protects pancreatic beta-cells from cytokine-mediated apoptosis and CD8+ T-cell-induced cytotoxicity.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Inhibition of AMP-activated pr ...... + T-cell-induced cytotoxicity.
@en
type
label
Inhibition of AMP-activated pr ...... + T-cell-induced cytotoxicity.
@en
prefLabel
Inhibition of AMP-activated pr ...... + T-cell-induced cytotoxicity.
@en
P2093
P356
P1433
P1476
Inhibition of AMP-activated pr ...... 8+ T-cell-induced cytotoxicity
@en
P2093
Audrey Riboulet-Chavey
Frédérique Diraison
Guy A Rutter
L Khai Siew
P304
P356
10.2337/DB07-0993
P407
P577
2007-11-14T00:00:00Z