DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B.
about
Targeted gene therapy of xeroderma pigmentosum cells using meganuclease and TALEN™Caspase 3/caspase-activated DNase promote cell differentiation by inducing DNA strand breaksA clinical-molecular update on azanucleoside-based therapy for the treatment of hematologic cancersTargeting epigenetic pathways in acute myeloid leukemia and myelodysplastic syndrome: a systematic review of hypomethylating agents trialsA poor imitation of a natural process: a call to reconsider the iPSC engineering technique5'-Cytosine-Phosphoguanine (CpG) Methylation Impacts the Activity of Natural and Engineered MeganucleasesOral Azacitidine (CC-486) for the Treatment of Myelodysplastic Syndromes and Acute Myeloid LeukemiaRoles of Chk1 in cell biology and cancer therapyA comparison of azacitidine and decitabine activities in acute myeloid leukemia cell linesIntegrative analysis of epigenetic modulation in melanoma cell response to decitabine: clinical implicationsChanges in global gene expression in response to chemical and genetic perturbation of chromatin structureDNA methyltransferase inhibitors improve the effect of chemotherapeutic agents in SW48 and HT-29 colorectal cancer cells5-Aza-2'-deoxycytidine increases sialyl Lewis X on MUC1 by stimulating β-galactoside:α2,3-sialyltransferase 6 gene.DNA-dependent protein kinase (DNA-PK)-deficient human glioblastoma cells are preferentially sensitized by Zebularine.Combination epigenetic therapy in metastatic colorectal cancer (mCRC) with subcutaneous 5-azacitidine and entinostat: a phase 2 consortium/stand up 2 cancer study.Epigenetics of induced pluripotency, the seven-headed dragonPhylogeny, expression patterns and regulation of DNA Methyltransferases in early development of the flatfish, Solea senegalensisHaplotypes of DNMT1 and DNMT3B are associated with mutagen sensitivity induced by benzo[a]pyrene diol epoxide among smokersDecitabine in the treatment of myelodysplastic syndromes.Leukaemogenesis: more than mutant genesDNA methyltransferases, DNA damage repair, and cancerOvercoming transcription activator-like effector (TALE) DNA binding domain sensitivity to cytosine methylation.Acute hypersensitivity of pluripotent testicular cancer-derived embryonal carcinoma to low-dose 5-aza deoxycytidine is associated with global DNA Damage-associated p53 activation, anti-pluripotency and DNA demethylation.DNA demethylating antineoplastic strategies: a comparative point of viewPemetrexed and gemcitabine as combination therapy for the treatment of Group3 medulloblastoma.The role of promoter methylation in Epstein-Barr virus (EBV) microRNA expression in EBV-infected B cell lines.Evaluation of noncytotoxic DNMT1-depleting therapy in patients with myelodysplastic syndromes.Epigenetic mechanisms and genome stability.Cancer epigenetics: linking basic biology to clinical medicine.Reprogramming epigenetic silencing: artificial transcription factors synergize with chromatin remodeling drugs to reactivate the tumor suppressor mammary serine protease inhibitor.The DNA methylation inhibitor induces telomere dysfunction and apoptosis of leukemia cells that is attenuated by telomerase over-expression.Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells.A comprehensive analysis of radiosensitization targets; functional inhibition of DNA methyltransferase 3B radiosensitizes by disrupting DNA damage regulation.Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutières syndrome.Single-cell, locus-specific bisulfite sequencing (SLBS) for direct detection of epimutations in DNA methylation patterns.FOXO3/FKHRL1 is activated by 5-aza-2-deoxycytidine and induces silenced caspase-8 in neuroblastoma5-aza-2'-deoxycytidine-induced genome rearrangements are mediated by DNMT1.DNA hypermethylation in hyperhomocysteinemia contributes to abnormal extracellular matrix metabolism in the kidneySpecific molecular signatures predict decitabine response in chronic myelomonocytic leukemia.Cancer-linked satellite 2 DNA hypomethylation does not regulate Sat2 non-coding RNA expression and is initiated by heat shock pathway activation
P2860
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P2860
DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
DNA methylation inhibitor 5-Az ...... A methyltransferases 1 and 3B.
@en
type
label
DNA methylation inhibitor 5-Az ...... A methyltransferases 1 and 3B.
@en
prefLabel
DNA methylation inhibitor 5-Az ...... A methyltransferases 1 and 3B.
@en
P2093
P2860
P356
P1476
DNA methylation inhibitor 5-Az ...... NA methyltransferases 1 and 3B
@en
P2093
Beth O Van Emburgh
Kevin D Brown
Stela S Palii
P2860
P304
P356
10.1128/MCB.01799-07
P407
P577
2007-11-08T00:00:00Z