ST6Gal-I protein expression is upregulated in human epithelial tumors and correlates with stem cell markers in normal tissues and colon cancer cell lines.
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The role of N-glycans in colorectal cancer progression: potential biomarkers and therapeutic applicationsEnzymatic Basis for N-Glycan Sialylation: STRUCTURE OF RAT 2,6-SIALYLTRANSFERASE (ST6GAL1) REVEALS CONSERVED AND UNIQUE FEATURES FOR GLYCAN SIALYLATIONReversal effect of ST6GAL 1 on multidrug resistance in human leukemia by regulating the PI3K/Akt pathway and the expression of P-gp and MRP1The Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell PhenotypeGenetic alterations in seborrheic keratoses.An oncogenic protein Golgi phosphoprotein 3 up-regulates cell migration via sialylation.β-Galactoside α2,6-sialyltranferase 1 promotes transforming growth factor-β-mediated epithelial-mesenchymal transition.Epigenetic inactivation of ST6GAL1 in human bladder cancer.Glycosyltransferase ST6GAL1 contributes to the regulation of pluripotency in human pluripotent stem cells.Sialic acid-modified antigens impose tolerance via inhibition of T-cell proliferation and de novo induction of regulatory T cells.ST6Gal-I sialyltransferase confers cisplatin resistance in ovarian tumor cells.Tetraspanin CD82 regulates bone marrow homing of acute myeloid leukemia by modulating the molecular organization of N-cadherinTumor sialylation impedes T cell mediated anti-tumor responses while promoting tumor associated-regulatory T cells.CD133: a stem cell biomarker and beyondST6Gal-I modulates docetaxel sensitivity in human hepatocarcinoma cells via the p38 MAPK/caspase pathway.Remodeling of marrow hematopoietic stem and progenitor cells by non-self ST6Gal-1 sialyltransferase.ST6Gal-I overexpression facilitates prostate cancer progression via the PI3K/Akt/GSK-3β/β-catenin signaling pathwayO-glycan sialylation alters galectin-3 subcellular localization and decreases chemotherapy sensitivity in gastric cancer.Elevation of β-galactoside α2,6-sialyltransferase 1 in a fructoseresponsive manner promotes pancreatic cancer metastasis.Complement inhibitor CSMD1 acts as tumor suppressor in human breast cancer.Increasing the α 2, 6 sialylation of glycoproteins may contribute to metastatic spread and therapeutic resistance in colorectal cancer.Significance of β-Galactoside α2,6 Sialyltranferase 1 in Cancers.The Glycosyltransferase ST6Gal-I Protects Tumor Cells against Serum Growth Factor Withdrawal by Enhancing Survival Signaling and Proliferative Potential.Glycosylation is an Androgen-Regulated Process Essential for Prostate Cancer Cell Viabilityα2,6-linked sialic acids on N-glycans modulate the adhesion of hepatocarcinoma cells to lymph nodes.Sialylation of N-glycans: mechanism, cellular compartmentalization and function.Gene expression profiling of anti-CTLA4-treated metastatic melanoma in patients with treatment-induced autoimmunity.Viewing Siglecs through the lens of tumor immunology.Cellular glycosylation senses metabolic changes and modulates cell plasticity during epithelial to mesenchymal transition.Cell type-specific glycosylation of Orai1 modulates store-operated Ca2+ entry.α2,6-linked sialic acid serves as a high-affinity receptor for cancer oncolytic virotherapy with Newcastle disease virus.α2,6-Sialylation mediates hepatocellular carcinoma growth in vitro and in vivo by targeting the Wnt/β-catenin pathway.ST8SIA4-Dependent Polysialylation is Part of a Developmental Program Required for Germ Layer Formation from Human Pluripotent Stem Cells.Hyperglycemia exacerbates colon cancer malignancy through hexosamine biosynthetic pathwayStructural and quantitative evidence of α2-6-sialylated N-glycans as markers of the differentiation potential of human mesenchymal stem cells.Transition state-based ST6Gal I inhibitors: Mimicking the phosphodiester linkage with a triazole or carbamate through an enthalpy-entropy compensation.Identification of proteins with the CDw75 epitope in human colorectal cancer.Drug resistance related to aberrant glycosylation in colorectal cancer.Sialylation of EGFR by the ST6Gal-I sialyltransferase promotes EGFR activation and resistance to gefitinib-mediated cell death.ST6Gal-I sialyltransferase promotes tumor necrosis factor (TNF)-mediated cancer cell survival via sialylation of the TNF receptor 1 (TNFR1) death receptor.
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P2860
ST6Gal-I protein expression is upregulated in human epithelial tumors and correlates with stem cell markers in normal tissues and colon cancer cell lines.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
ST6Gal-I protein expression is ...... s and colon cancer cell lines.
@en
type
label
ST6Gal-I protein expression is ...... s and colon cancer cell lines.
@en
prefLabel
ST6Gal-I protein expression is ...... s and colon cancer cell lines.
@en
P2093
P2860
P1433
P1476
ST6Gal-I protein expression is ...... es and colon cancer cell lines
@en
P2093
Amanda F Swindall
Angelina I Londoño-Joshi
Matthew J Schultz
Naomi Fineberg
Susan L Bellis
P2860
P304
P356
10.1158/0008-5472.CAN-12-3424
P407
P577
2013-01-28T00:00:00Z