The p160 nuclear receptor co-activator RAC3 exerts an anti-apoptotic role through a cytoplasmatic action.
about
New targets for the antitumor activity of gambogic acid in hematologic malignanciesSRC-3 has a role in cancer other than as a nuclear receptor coactivator.Subcellular rearrangement of hsp90-binding immunophilins accompanies neuronal differentiation and neurite outgrowthApoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF-κB pathwayIncreased radiosensitivity and radiation-induced apoptosis in SRC-3 knockout mice.Impaired hematopoiesis and delayed thrombopoietic recovery following sublethal irradiation in SRC‑3 knockout mice.The levels of RAC3 expression are up regulated by TNF in the inflammatory response.NF-κB transcriptional activity is modulated by FK506-binding proteins FKBP51 and FKBP52: a role for peptidyl-prolyl isomerase activity.Management of cytoskeleton architecture by molecular chaperones and immunophilins.The 90-kDa heat-shock protein (Hsp90)-binding immunophilin FKBP51 is a mitochondrial protein that translocates to the nucleus to protect cells against oxidative stress.RAC3 more than a nuclear receptor coactivator: a key inhibitor of senescence that is downregulated in aging.The role of AIB1 in breast cancerRegulation of the glucocorticoid response to stress-related disorders by the Hsp90-binding immunophilin FKBP51.Hsp90-binding immunophilins as a potential new platform for drug treatment.Biological relevance of Hsp90-binding immunophilins in cancer development and treatment.HSP90AB1: Helping the good and the bad.Nuclear receptor coactivator RAC3 inhibits autophagy.Gambogic acid induces mitochondria-dependent apoptosis by modulation of Bcl-2 and Bax in mantle cell lymphoma JeKo-1 cells.Hsp90-binding immunophilin FKBP51 forms complexes with hTERT enhancing telomerase activity.Overexpression of AIB1 correlates inversely with E-cadherin expression in pancreatic adenocarcinoma and may promote lymph node metastasis.RAC3 influences the chemoresistance of colon cancer cells through autophagy and apoptosis inhibition.High RAC3 expression levels are required for induction and maintaining of cancer cell stemness.
P2860
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P2860
The p160 nuclear receptor co-activator RAC3 exerts an anti-apoptotic role through a cytoplasmatic action.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The p160 nuclear receptor co-a ...... hrough a cytoplasmatic action.
@en
type
label
The p160 nuclear receptor co-a ...... hrough a cytoplasmatic action.
@en
prefLabel
The p160 nuclear receptor co-a ...... hrough a cytoplasmatic action.
@en
P2093
P2860
P50
P356
P1433
P1476
The p160 nuclear receptor co-a ...... through a cytoplasmatic action
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210900
P407
P577
2007-10-29T00:00:00Z
P5875
P6179
1035593230