Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance.
about
Regulatory T cell suppressive potency dictates the balance between bacterial proliferation and clearance during persistent Salmonella infectionCTLs respond with activation and granule secretion when serving as targets for T-cell recognitionThe PD-1 pathway in tolerance and autoimmunityFunctional Mechanisms of Treg in the Context of HIV Infection and the Janus Face of Immune SuppressionThymic and Postthymic Regulation of Naïve CD4(+) T-Cell Lineage Fates in Humans and Mice ModelsUntil Death Do Us Part: Necrosis and Oxidation Promote the Tumor MicroenvironmentRegulatory T Cells: Molecular Actions on Effector Cells in Immune RegulationGenetics and biology of pancreatic ductal adenocarcinomaNK Cell and CD4+FoxP3+ Regulatory T Cell Based Therapies for Hematopoietic Stem Cell EngraftmentTranslating Treg Therapy in Humanized MiceInducing and Administering Tregs to Treat Human DiseaseDisrupted regulatory T cell homeostasis in inflammatory bowel diseasesExploiting the Immunomodulatory Properties of Chemotherapeutic Drugs to Improve the Success of Cancer ImmunotherapyFOXP3(+) Treg Cells and Gender Bias in Autoimmune DiseasesUnderstanding the interplay between host immunity and Epstein-Barr virus in NPC patientsRegulatory T cells: Mechanisms of suppression and impairment in autoimmune liver diseaseCytotoxic CD4 T Cells: Differentiation, Function, and Application to Dengue Virus InfectionUnderstanding of molecular mechanisms in natural killer cell therapyHow regulatory T cells workRegulatory T cells: mechanisms of differentiation and functionGranzyme B produced by human plasmacytoid dendritic cells suppresses T-cell expansion.A20 Haploinsufficiency Aggravates Transplant Arteriosclerosis in Mouse Vascular Allografts: Implications for Clinical Transplantation.Induction of granzyme B expression in T-cell receptor/CD28-stimulated human regulatory T cells is suppressed by inhibitors of the PI3K-mTOR pathway.Once a Treg, always a Treg?Improved HSC reconstitution and protection from inflammatory stress and chemotherapy in mice lacking granzyme B.Different subsets of tumor infiltrating lymphocytes correlate with NPC progression in different ways.Redox remodeling as an immunoregulatory strategy.A different representation of natural T cells and natural killer cells between tumor-infiltrating and periphery lymphocytes in human hepatocellular carcinoma.Granzyme B is not required for regulatory T cell-mediated suppression of graft-versus-host disease.Lymphocytes in cancer development: polarization towards pro-tumor immunityGenes related to antiviral activity, cell migration, and lysis are differentially expressed in CD4(+) T cells in human t cell leukemia virus type 1-associated myelopathy/tropical spastic paraparesis patients.Generation and accumulation of immunosuppressive adenosine by human CD4+CD25highFOXP3+ regulatory T cells.Ncf1 (p47phox) is essential for direct regulatory T cell mediated suppression of CD4+ effector T cells.Lkb1 maintains Treg cell lineage identity.Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responsesIn situ vaccination combined with androgen ablation and regulatory T-cell depletion reduces castration-resistant tumor burden in prostate-specific pten knockout mice.Intraepithelial effector (CD3+)/regulatory (FoxP3+) T-cell ratio predicts a clinical outcome of human colon carcinomaLow-dose cyclophosphamide synergizes with dendritic cell-based immunotherapy in antitumor activity.Adaptive control of innate immunity.In vivo administration of hypomethylating agents mitigate graft-versus-host disease without sacrificing graft-versus-leukemia.
P2860
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P2860
Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Granzyme B and perforin are im ...... uppression of tumor clearance.
@en
type
label
Granzyme B and perforin are im ...... uppression of tumor clearance.
@en
prefLabel
Granzyme B and perforin are im ...... uppression of tumor clearance.
@en
P2093
P1433
P1476
Granzyme B and perforin are im ...... uppression of tumor clearance.
@en
P2093
David R Piwnica-Worms
Jiling Song
Lynne I Collins
Sheng F Cai
Timothy J Ley
Todd A Fehniger
Xuefang Cao
P304
P356
10.1016/J.IMMUNI.2007.08.014
P407
P577
2007-10-04T00:00:00Z