Valproic acid enhances tubulin acetylation and apoptotic activity of paclitaxel on anaplastic thyroid cancer cell lines.
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Novel histone deacetylase inhibitors in clinical trials as anti-cancer agentsThe novel tubulin polymerization inhibitor MHPT exhibits selective anti-tumor activity against rhabdomyosarcoma in vitro and in vivoCell type-specific anti-cancer properties of valproic acid: independent effects on HDAC activity and Erk1/2 phosphorylationLack of therapeutic effect of the histone deacetylase inhibitor vorinostat in patients with metastatic radioiodine-refractory thyroid carcinomaRapamycin potentiates the effects of paclitaxel in endometrial cancer cells through inhibition of cell proliferation and induction of apoptosis.Anaplastic thyroid cancer: molecular pathogenesis and emerging therapies.Paxillin inhibits HDAC6 to regulate microtubule acetylation, Golgi structure, and polarized migration.Histone deacetylase: a potential therapeutic target for fibrotic disordersEffects of valproic acid on the cell cycle and apoptosis through acetylation of histone and tubulin in a scirrhous gastric cancer cell lineNovel approaches in anaplastic thyroid cancer therapyOncogenic Actions of the Nuclear Receptor Corepressor (NCOR1) in a Mouse Model of Thyroid Cancer.Utility of a histone deacetylase inhibitor (PXD101) for thyroid cancer treatment.Emerging therapeutics for advanced thyroid malignancies: rationale and targeted approaches.Randomized Phase II trial of paclitaxel plus valproic acid vs paclitaxel alone as second-line therapy for patients with advanced gastric cancer.Targeted therapies for non-small cell lung cancer: an evolving landscape.Epigenetics modifications and therapeutic prospects in human thyroid cancer.RhoB upregulation leads to either apoptosis or cytostasis through differential target selection.Valproic acid inhibits proliferation of HER2-expressing breast cancer cells by inducing cell cycle arrest and apoptosis through Hsp70 acetylationEpigenetic regulation of CD8(+) T-lymphocyte mediated suppression of HIV-1 replicationHistone deacetylase inhibitors in lymphoma and solid malignancies.Paclitaxel plus valproic acid versus paclitaxel alone as second- or third-line therapy for advanced gastric cancer: a randomized Phase II trialThe role of chemotherapy and latest emerging target therapies in anaplastic thyroid cancer.Valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, diminishes lymphoproliferation in the Fas -deficient MRL/lpr(-/-) murine model of autoimmune lymphoproliferative syndrome (ALPS)Valproic Acid, a Histone Deacetylase Inhibitor, in Combination with Paclitaxel for Anaplastic Thyroid Cancer: Results of a Multicenter Randomized Controlled Phase II/III Trial.Disruption of normal cytoskeletal dynamics may play a key role in the pathogenesis of epilepsy.Selective HDAC inhibition by ACY-241 enhances the activity of paclitaxel in solid tumor models.Anaplastic thyroid cancer: a comprehensive review of novel therapy.Targeting histone deacetylase in thyroid cancer.Histone Deacetylase Inhibitors as Anticancer Drugs.Histone deacetylase 3 indirectly modulates tubulin acetylationInduction of apoptosis and autophagy in metastatic thyroid cancer cells by valproic acid (VPA).The heat shock protein 90 inhibitor SNX5422 has a synergistic activity with histone deacetylase inhibitors in induction of death of anaplastic thyroid carcinoma cells.Synergy between HDAC and PARP Inhibitors on Proliferation of a Human Anaplastic Thyroid Cancer-Derived Cell Line.The effect of 17-allylamino-17-demethoxygeldanamycin alone or in combination with paclitaxel on anaplastic thyroid carcinoma cells.Valproic acid induced differentiation and potentiated efficacy of taxol and nanotaxol for controlling growth of human glioblastoma LN18 and T98G cells.The teratogenic potencies of valproic acid derivatives and their effects on biological end-points are related to changes in histone deacetylase and Erk1/2 activities.Cytotoxic activity of the histone deacetylase inhibitor panobinostat (LBH589) in anaplastic thyroid cancer in vitro and in vivo.The impact of amyloid precursor protein signalling and histone deacetylase inhibition on neprilysin expression in human prostate cells.In vitro anticancer drug test: A new method emerges from the model of glioma stem cells.Valproic Acid Regulates α-Synuclein Expression through JNK Pathway in Rat Primary Astrocytes
P2860
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P2860
Valproic acid enhances tubulin acetylation and apoptotic activity of paclitaxel on anaplastic thyroid cancer cell lines.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Valproic acid enhances tubulin ...... tic thyroid cancer cell lines.
@en
type
label
Valproic acid enhances tubulin ...... tic thyroid cancer cell lines.
@en
prefLabel
Valproic acid enhances tubulin ...... tic thyroid cancer cell lines.
@en
P2093
P356
P1476
Valproic acid enhances tubulin ...... stic thyroid cancer cell lines
@en
P2093
Giuseppe Boccuzzi
Mariateresa Pugliese
Roberta Poli
P304
P356
10.1677/ERC-07-0096
P577
2007-09-01T00:00:00Z