Direct regulation of the minichromosome maintenance complex by MYCN in neuroblastoma.
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MicroRNA-184 inhibits neuroblastoma cell survival through targeting the serine/threonine kinase AKT2A p53 drug response signature identifies prognostic genes in high-risk neuroblastomaGlobal MYCN transcription factor binding analysis in neuroblastoma reveals association with distinct E-box motifs and regions of DNA hypermethylation.Unveiling MYCN regulatory networks in neuroblastoma via integrative analysis of heterogeneous genomics data.Ultraviolet radiation stress triggers the down-regulation of essential replication factor Mcm10.Genetic demonstration of a redundant role of extracellular signal-regulated kinase 1 (ERK1) and ERK2 mitogen-activated protein kinases in promoting fibroblast proliferationCo-localization of the oncogenic transcription factor MYCN and the DNA methyl binding protein MeCP2 at genomic sites in neuroblastoma.Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation.Interaction of integrin-linked kinase and miniature chromosome maintenance 7-mediating integrin {alpha}7 induced cell growth suppression.Functional MYCN signature predicts outcome of neuroblastoma irrespective of MYCN amplification.Neuroblastoma and MYCNInactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells.Role of Myc in hepatocellular proliferation and hepatocarcinogenesis.TRIM8 restores p53 tumour suppressor function by blunting N-MYC activity in chemo-resistant tumours.Enigmatic roles of Mcm10 in DNA replicationMCM10: one tool for all-Integrity, maintenance and damage control.Dissection of the oncogenic MYCN transcriptional network reveals a large set of clinically relevant cell cycle genes as drivers of neuroblastoma tumorigenesis.Overexpression of minichromosome maintenance protein 10 in medulloblastoma and its clinical implications.Monocyte Chemoattractant Protein-Induced Protein 1 Overexpression Modulates Transcriptome, Including MicroRNA, in Human Neuroblastoma Cells.Mcm10: A Dynamic Scaffold at Eukaryotic Replication ForksCopy number defects of G1-cell cycle genes in neuroblastoma are frequent and correlate with high expression of E2F target genes and a poor prognosis.MCM7 expression is altered in rat after spinal cord injury.C-Myc-dependent repression of two oncogenic miRNA clusters contributes to triptolide-induced cell death in hepatocellular carcinoma cells.DNA Replication Licensing Protein MCM10 Promotes Tumor Progression and Is a Novel Prognostic Biomarker and Potential Therapeutic Target in Breast Cancer
P2860
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P2860
Direct regulation of the minichromosome maintenance complex by MYCN in neuroblastoma.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Direct regulation of the minichromosome maintenance complex by MYCN in neuroblastoma.
@en
type
label
Direct regulation of the minichromosome maintenance complex by MYCN in neuroblastoma.
@en
prefLabel
Direct regulation of the minichromosome maintenance complex by MYCN in neuroblastoma.
@en
P2093
P50
P1476
Direct regulation of the minichromosome maintenance complex by MYCN in neuroblastoma.
@en
P2093
Arjen Koppen
Huib N Caron
Linda J Valentijn
Peter G van Sluis
Rachida Ait-Aissa
Richard Volckmann
P304
P356
10.1016/J.EJCA.2007.07.024
P577
2007-09-10T00:00:00Z