Valproic acid activates notch-1 signaling and regulates the neuroendocrine phenotype in carcinoid cancer cells. - Wikidata - wikimedia - TriplyDB

Valproic acid activates notch-1 signaling and regulates the neuroendocrine phenotype in carcinoid cancer cells.

Valproic acid activates notch-1 signaling and regulates the neuroendocrine phenotype in carcinoid cancer cells.

http://www.wikidata.org/entity/Q40086013

about

Guidance molecules in lung cancer Clonal Expansion of Lgr5-Positive Cells from Mammalian Cochlea and High-Purity Generation of Sensory Hair Cells Histone deacetylase activity selectively regulates notch-mediated smooth muscle differentiation in human vascular cells.A Phase II Trial of a Histone Deacetylase Inhibitor Panobinostat in Patients With Low-Grade Neuroendocrine Tumors Notch in the development of thyroid C-cells and the treatment of medullary thyroid cancer.Inhibition of growth in medullary thyroid cancer cells with histone deacetylase inhibitors and lithium chloride.Intermittent activation of notch signaling promotes bone formation.Integration of signals along orthogonal axes of the vertebrate neural tube controls progenitor competence and increases cell diversity Valproic acid induces Notch1 signaling in small cell lung cancer cells Valproic acid activates Notch1 signaling and induces apoptosis in medullary thyroid cancer cells Influence of glutamine on transient and stable recombinant protein production in CHO and HEK-293 cells.Identification of small molecule Hes1 modulators as potential anticancer chemotherapeutics.Signaling mechanisms in neuroendocrine tumors as targets for therapy.Xanthohumol inhibits the neuroendocrine transcription factor achaete-scute complex-like 1, suppresses proliferation, and induces phosphorylated ERK1/2 in medullary thyroid cancer.Identification and validation of Notch pathway activating compounds through a novel high-throughput screening method.A pilot phase II study of valproic acid for treatment of low-grade neuroendocrine carcinoma.Expression of the active Notch1 decreases MTC tumor growth in vivo.Notch1-mediated tumor suppression in cervical cancer with the involvement of SST signaling and its application in enhanced SSTR-targeted therapeutics.Thailandepsin A-loaded and octreotide-functionalized unimolecular micelles for targeted neuroendocrine cancer therapy.Valproic acid downregulates the expression of MGMT and sensitizes temozolomide-resistant glioma cells.The Histone Deacetylase Inhibitor Vaproic Acid Induces Cell Growth Arrest in Hepatocellular Carcinoma Cells via Suppressing Notch Signaling.Chrysin suppresses achaete-scute complex-like 1 and alters the neuroendocrine phenotype of carcinoids.Potential Therapeutic Role of Z-Isochaihulactone in Lung Cancer through Induction of Apoptosis via Notch Signaling.Anti-tumor effects of the Notch pathway in gastrointestinal stromal tumors Synergistic effect of pasireotide and teriflunomide in carcinoids in vitro.Cancer stem cells and the ontogeny of lung cancer Histone deacetylase inhibitors upregulate Notch-1 and inhibit growth in pheochromocytoma cells Tautomycetin and tautomycin suppress the growth of medullary thyroid cancer cells via inhibition of glycogen synthase kinase-3beta.Notch1 mediates growth suppression of papillary and follicular thyroid cancer cells by histone deacetylase inhibitors.Novel targets for the treatment and palliation of gastrointestinal neuroendocrine tumors Suberoyl bishydroxamic acid activates notch1 signaling and suppresses tumor progression in an animal model of medullary thyroid carcinoma.Combination therapy with histone deacetylase inhibitors and lithium chloride: a novel treatment for carcinoid tumors.Sodium butyrate activates Notch1 signaling, reduces tumor markers, and induces cell cycle arrest and apoptosis in pheochromocytoma.Valproic acid silencing of ascl1b/Ascl1 results in the failure of serotonergic differentiation in a zebrafish model of fetal valproate syndrome Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny.Selected pharmacokinetic issues of the use of antiepileptic drugs and parenteral nutrition in critically ill patients.The molecular pathogenesis and management of bronchial carcinoids.Signaling pathways as specific pharmacologic targets for neuroendocrine tumor therapy: RET, PI3K, MEK, growth factors, and Notch.The role of cell lines in the study of neuroendocrine tumors.Current understanding of the molecular biology of pancreatic neuroendocrine tumors.

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P2860

Valproic acid activates notch-1 signaling and regulates the neuroendocrine phenotype in carcinoid cancer cells.

http://www.wikidata.org/entity/Q40086013

description

2007 nî lūn-bûn

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2007年论文

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2007年论文

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name

Valproic acid activates notch- ...... ype in carcinoid cancer cells.

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Valproic acid activates notch- ...... ype in carcinoid cancer cells.

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THEONCOLOGIST.12-8-942

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Abram M Vaccaro

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David Yu Greenblatt

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Herbert Chen

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Li Ning

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Megan Haymart

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Muthusamy Kunnimalaiyaan

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942-951

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scholarly article

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10.1634/THEONCOLOGIST.12-8-942

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