Group A streptococcus activates type I interferon production and MyD88-dependent signaling without involvement of TLR2, TLR4, and TLR9.
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Immune evasion and recognition of the syphilis spirochete in blood and skin of secondary syphilis patients: two immunologically distinct compartmentsInflammasome/IL-1β Responses to Streptococcal PathogensPhagosomal signaling by Borrelia burgdorferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-betaThe innate immune response elicited by Group A Streptococcus is highly variable among clinical isolates and correlates with the emm type.Activation of human monocytes by live Borrelia burgdorferi generates TLR2-dependent and -independent responses which include induction of IFN-beta.Borrelia burgdorferi RNA induces type I and III interferons via Toll-like receptor 7 and contributes to production of NF-κB-dependent cytokinesBifidobacterium bifidum actively changes the gene expression profile induced by Lactobacillus acidophilus in murine dendritic cells.Type I interferon production induced by Streptococcus pyogenes-derived nucleic acids is required for host protectionMyD88 and STING signaling pathways are required for IRF3-mediated IFN-β induction in response to Brucella abortus infectionResponses of innate immune cells to group A Streptococcus.Macrophages recognize streptococci through bacterial single-stranded RNAA critical role for type I IFN in arthritis development following Borrelia burgdorferi infection of mice.Streptococcus pneumoniae DNA initiates type I interferon signaling in the respiratory tractInnate immune response to Streptococcus pyogenes depends on the combined activation of TLR13 and TLR2.Host responses to group a streptococcus: cell death and inflammationPostpartum group a Streptococcus sepsis and maternal immunology.NO is a macrophage autonomous modifier of the cytokine response to streptococcal single-stranded RNAImportance of Toll-like receptor 9 in host defense against M1T1 group A Streptococcus infectionsA MyD88-JAK1-STAT1 complex directly induces SOCS-1 expression in macrophages infected with Group A Streptococcus.Failure to induce IFN-β production during Staphylococcus aureus infection contributes to pathogenicity.Regulatory role of GSK-3 β on NF- κ B, nitric oxide, and TNF- α in group A streptococcal infection.Exacerbated type II interferon response drives hypervirulence and toxic shock by an emergent epidemic strain of Streptococcus suisCDK8-mediated STAT1-S727 phosphorylation restrains NK cell cytotoxicity and tumor surveillanceActivation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor.The Emerging Roles of STING in Bacterial Infections.The role of innate immune signals in immunity to Brucella abortus.Subterfuge and sabotage: evasion of host innate defenses by invasive gram-positive bacterial pathogens.Lactobacillus acidophilus induces virus immune defence genes in murine dendritic cells by a Toll-like receptor-2-dependent mechanism.Superoxide anions produced by Streptococcus pyogenes group A-stimulated keratinocytes are responsible for cellular necrosis and bacterial growth inhibition.Group A Streptococcus emm3 strains induce early macrophage cell death.The Lyme disease spirochete Borrelia burgdorferi utilizes multiple ligands, including RNA, for interferon regulatory factor 3-dependent induction of type I interferon-responsive genesA critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome.Invasive group A Streptococcus disease in French-Canadian children is not associated with a defect in MyD88/IRAK4-pathwayDynamin inhibition interferes with inflammasome activation and cytokine gene expression in Streptococcus pyogenes-infected human macrophages.Aberrant inflammatory response to Streptococcus pyogenes in mice lacking myeloid differentiation factor 88.Group A Streptococcus encounters with host macrophages.Streptococcal M protein promotes IL-10 production by cGAS-independent activation of the STING signaling pathway.Mechanisms of TNF induction by heat-killed Staphylococcus aureus differ upon the origin of mononuclear phagocytes.Dextromethorphan Attenuates NADPH Oxidase-Regulated Glycogen Synthase Kinase 3β and NF-κB Activation and Reduces Nitric Oxide Production in Group A Streptococcal Infection.The Bicarbonate Transporter SLC4A7 Plays a Key Role in Macrophage Phagosome Acidification.
P2860
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P2860
Group A streptococcus activates type I interferon production and MyD88-dependent signaling without involvement of TLR2, TLR4, and TLR9.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Group A streptococcus activate ...... ement of TLR2, TLR4, and TLR9.
@en
type
label
Group A streptococcus activate ...... ement of TLR2, TLR4, and TLR9.
@en
prefLabel
Group A streptococcus activate ...... ement of TLR2, TLR4, and TLR9.
@en
P2093
P2860
P356
P1476
Group A streptococcus activate ...... ement of TLR2, TLR4, and TLR9.
@en
P2093
Barbara Schaljo
Carsten J Kirschning
Hermann Wagner
Irene Gattermeier
Ivo Vojtek
Maria Siller
Nina Gratz
Shizuo Akira
Zaid A Pirzada
P2860
P304
19879-19887
P356
10.1074/JBC.M802848200
P407
P577
2008-05-14T00:00:00Z