Adenylate cyclase-coupled beta-adrenergic receptors: structure and mechanisms of activation and desensitization.
about
Chromosomal organization of adrenergic receptor genesDifferentiation-inducing factor from the slime mould Dictyostelium discoideum and its analogues. Synthesis, structure and biological activitycDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factorParoxetine Is a Direct Inhibitor of G Protein-Coupled Receptor Kinase 2 and Increases Myocardial ContractilityGhrelin.Acute change in the cyclic AMP content of rat mammary acini in vitro. Influence of physiological and pharmacological agentsMolecular insights into the dynamics of pharmacogenetically important N-terminal variants of the human β2-adrenergic receptorIsoproterenol response following transfection of the mouse beta 2-adrenergic receptor gene into Y1 cellsBeta-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptorOligodendrocyte substratum adhesion modulates expression of adenylate cyclase-linked receptors.Congestive heart failure. New frontiersDifferential regulations of vestibulo-ocular reflex and optokinetic response by β- and α2-adrenergic receptors in the cerebellar flocculus.A novel action of isoproterenol to inactivate a cardiac K+ current is not blocked by beta and alpha adrenergic blockers.Beta adrenergic receptor blockade of feline myocardium. Cardiac mechanics, energetics, and beta adrenoceptor regulation.Identification of residues required for ligand binding to the beta-adrenergic receptor.In vivo desensitization of glycogenolysis to Ca2+-mobilizing hormones in rat liver cells.Desensitization of adenosine receptor-mediated inhibition of lipolysis. The mechanism involves the development of enhanced cyclic adenosine monophosphate accumulation in tolerant adipocytesAdrenoceptor- and cholinoceptor-mediated mechanisms in the regulation of 5-hydroxytryptamine release from isolated tracheae of newborn rabbits.Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors.Biochemical and functional responses stimulated by platelet-activating factor in murine peritoneal macrophages.Phorbol ester induces desensitization of adenylate cyclase and phosphorylation of the beta-adrenergic receptor in turkey erythrocytesStructure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine.Augmentation of macrophage complement receptor function in vitro. IV. The lymphokine that activates macrophage C3 receptors for phagocytosis binds to a fucose-bearing glycoprotein on the macrophage plasma membrane.Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.Platelet-derived growth factor-stimulated c-myc RNA accumulation in MG-63 human osteosarcoma cells is independent of both protein kinase A and protein kinase C.Structural insights and functional implications of inter-individual variability in β2-adrenergic receptorLong-term exposure to PGE2 causes homologous desensitization of receptor-mediated activation of protein kinase A.Overexpression of myocardial Gsalpha prevents full expression of catecholamine desensitization despite increased beta-adrenergic receptor kinase.Cyclic AMP mediates the direct antiproliferative action of mismatched double-stranded RNA.Beta-agonist- and prostaglandin E1-induced translocation of the beta-adrenergic receptor kinase: evidence that the kinase may act on multiple adenylate cyclase-coupled receptors.Role of calcium and EPAC in norepinephrine-induced ghrelin secretion.Rational design of receptor-specific variants of human growth hormone.Structural similarities between the mammalian beta-adrenergic and reovirus type 3 receptors.Influence of the beta-adrenergic receptor concentration on functional coupling to the adenylate cyclase system.Plasma catecholamines: laboratory aspects.Lateral mobility of proteins and lipids in the red cell membrane and the activation of adenylate cyclase by beta-adrenergic receptors.Regulation of M2, M3, and M4 muscarinic receptor expression in K562 chronic myelogenous leukemic cells by carbachol.Gaining access to the cytosol: the technique and some applications of electropermeabilization.Measles virus modulates human T-cell somatostatin receptors and their coupling to adenylyl cyclasePlasma membrane receptors.
P2860
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P2860
Adenylate cyclase-coupled beta-adrenergic receptors: structure and mechanisms of activation and desensitization.
description
1983 nî lūn-bûn
@nan
1983年の論文
@ja
1983年論文
@yue
1983年論文
@zh-hant
1983年論文
@zh-hk
1983年論文
@zh-mo
1983年論文
@zh-tw
1983年论文
@wuu
1983年论文
@zh
1983年论文
@zh-cn
name
Adenylate cyclase-coupled beta ...... ctivation and desensitization.
@en
type
label
Adenylate cyclase-coupled beta ...... ctivation and desensitization.
@en
prefLabel
Adenylate cyclase-coupled beta ...... ctivation and desensitization.
@en
P2093
P1476
Adenylate cyclase-coupled beta ...... ctivation and desensitization.
@en
P2093
P304
P356
10.1146/ANNUREV.BI.52.070183.001111
P577
1983-01-01T00:00:00Z