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p63 Expression in Merkel Cell Carcinoma Predicts Poorer Survival yet May Have Limited Clinical UtilityPD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma.31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part oneATR Regulates Fragile Site StabilityDiagnostic biopsy does not commonly induce intratumoral CD8 T cell infiltration in Merkel cell carcinoma.Merkel cell carcinoma adjuvant therapy: current data support radiation but not chemotherapy.Chemical genetics: elucidating biological systems with small-molecule compounds.Merkel cell polyomavirus is not detected in prostate cancers, surrounding stroma, or benign prostate controlsEpigenetic priming restores the HLA class-I antigen processing machinery expression in Merkel cell carcinomaInhibition of UVB-induced nonmelanoma skin cancer: a path from tea to caffeine to exercise to decreased tissue fatChemical methodology as a source of small-molecule checkpoint inhibitors and heat shock protein 70 (Hsp70) modulators.Transcriptome-wide studies of merkel cell carcinoma and validation of intratumoral CD8+ lymphocyte invasion as an independent predictor of survival.Asymmetric lateral distribution of melanoma and Merkel cell carcinoma in the United States.Merkel cell carcinoma associated with HIV: review of 14 patients.Merkel cell polyomavirus-specific CD8⁺ and CD4⁺ T-cell responses identified in Merkel cell carcinomas and blood.Caffeine decreases phospho-Chk1 (Ser317) and increases mitotic cells with cyclin B1 and caspase 3 in tumors from UVB-treated miceSurgical removal of the parametrial fat pads stimulates apoptosis and inhibits UVB-induced carcinogenesis in mice fed a high-fat dietA new American Joint Committee on Cancer staging system for cutaneous squamous cell carcinoma: creation and rationale for inclusion of tumor (T) characteristics.Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features.Effect of caffeine on the ATR/Chk1 pathway in the epidermis of UVB-irradiated mice.Pathologic nodal evaluation is increasingly commonly performed for patients with Merkel cell carcinoma.Human immunodeficiency virus type 1 Vpr-mediated G2 arrest requires Rad17 and Hus1 and induces nuclear BRCA1 and gamma-H2AX focus formation.Clinical utility of a circulating tumor cell assay in Merkel cell carcinomaImmunobiology of Merkel cell carcinoma: implications for immunotherapy of a polyomavirus-associated cancer.Emerging and mechanism-based therapies for recurrent or metastatic Merkel cell carcinomaATR is not required for p53 activation but synergizes with p53 in the replication checkpoint.Identification and validation of a novel mature microRNA encoded by the Merkel cell polyomavirus in human Merkel cell carcinomas.Paraneoplastic syndromes (PNS) associated with Merkel cell carcinoma (MCC): A case series of 8 patients highlighting different clinical manifestations.Merkel cell carcinoma: more deaths but still no pathway to blame.Merkel cell polyomavirus large T antigen has growth-promoting and inhibitory activitiesActivation of the ATR-mediated DNA damage response by the HIV-1 viral protein R.Interleukin-2 transcriptional block by multifunctional Ca2+/calmodulin kinase.Regression of metastatic Merkel cell carcinoma following transfer of polyomavirus-specific T cells and therapies capable of re-inducing HLA class-IMerkel cell polyomavirus is more frequently present in North American than Australian Merkel cell carcinoma tumors.Tumor-specific T cells in human Merkel cell carcinomas: a possible role for Tregs and T-cell exhaustion in reducing T-cell responses.Merkel polyomavirus-specific T cells fluctuate with merkel cell carcinoma burden and express therapeutically targetable PD-1 and Tim-3 exhaustion markersBasal cell and squamous cell skin cancers.Radiation monotherapy as regional treatment for lymph node-positive Merkel cell carcinoma.Case 19-2008: Merkel-cell carcinoma.Osteopontin is linked with AKT, FoxO1, and myostatin in skeletal muscle cells.
P50
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P50
description
hulumtues
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onderzoeker
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հետազոտող
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name
Paul Nghiem
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Paul Nghiem
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Paul Nghiem
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Paul Nghiem
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Paul Nghiem
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Paul Nghiem
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Paul Nghiem
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Paul Nghiem
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Paul Nghiem
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Paul Nghiem
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Paul Nghiem
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Paul Nghiem
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P106
P21
P31
P496
0000-0003-2784-963X