about
Solution structure of the ActD-5'-CCGTT3GTGG-3' complex: drug interaction with tandem G.T mismatches and hairpin loop backboneNatural compounds in the human diet and their ability to bind mutagens prevents DNA-mutagen intercalationChemical carcinogens: a review of the science and its associated principles. U.S. Interagency Staff Group on CarcinogensSelf-catalyzed cyclization of the intervening sequence RNA of Tetrahymena: inhibition by intercalating dyesSpecific inhibition of transcription by triple helix-forming oligonucleotidesBacteriophage T4 DNA topoisomerase is the target of antitumor agent 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA) in T4-infected Escherichia coliDNA-Destabilizing Agents as an Alternative Approach for Targeting DNA: Mechanisms of Action and Cellular ConsequencesPolymorphic nucleic Acid binding of bioactive isoquinoline alkaloids and their role in cancer.Therapeutic potential of nucleic acid-binding isoquinoline alkaloids: binding aspects and implications for drug design.Sequence specific binding of beta carboline alkaloid harmalol with deoxyribonucleotides: binding heterogeneity, conformational, thermodynamic and cytotoxic aspects.A thiazole coumarin (TC) turn-on fluorescence probe for AT-base pair detection and multipurpose applications in different biological systems.Topoisomerase II binds to ellipticine in the absence or presence of DNA. Characterization of enzyme-drug interactions by fluorescence spectroscopy.Actinomycin D induces high-level resistance to thymidine analogs in replication of human immunodeficiency virus type 1 by interfering with host cell thymidine kinase expression.Structure-based DNA-targeting strategies with small molecule ligands for drug discovery.DNA unwinding and inhibition of mouse leukemia L1210 DNA topoisomerase I by intercalators.Free-radical-mediated DNA bindingGenotoxicity of tri- and hexavalent chromium compounds in vivo and their modes of action on DNA damage in vitro.Viscometric analysis of the interaction of bisphenanthridinium compounds with closed circular supercoiled and linear DNA.Calorimetric and spectroscopic investigation of drug-DNA interactions. I. The binding of netropsin to poly d(AT).Daunomycin modifies the sequence-selective recognition of DNA by actinomycin.Differences in unwinding of supercoiled DNA induced by the two enantiomers of anti-benzo[a]pyrene diol epoxide.Apoptotic cells can deliver chemotherapeutics to engulfing macrophages and suppress inflammatory cytokine production.9-[(10-(aden-9-yl)-4,8-diazadecyl)amino]-6-chloro-2-methoxy-acridine incises DNA at apurinic sitesTargeting E2F1-DNA complexes with microgonotropen DNA binding agents.Interactions of water-soluble metalloporphyrins with nucleic acids studied by resonance Raman spectroscopy.A theoretical investigation on the sequence selective binding of adriamycin to double-stranded polynucleotides.Exploiting circular DNAMechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide.DNA-damaging activity of patulin in Escherichia coli.The solution structure of a 3'-phenazinium (Pzn) tethered DNA-RNA duplex with a dangling adenosine: r(5'G-AUUGAA3'):d(5'TCAATC3'-Pzn)The nature of actinomycin D binding to d(AACCAXYG) sequence motifsOptical tweezers experiments resolve distinct modes of DNA-protein binding.Nuclease activity of 1,10-phenanthroline-copper: sequence-specific targetingBinding of ethidium bromide causes dissociation of the nucleosome core particle.Cell cycle-dependent intervention by benzamide of carcinogen-induced neoplastic transformation and in vitro poly(ADP-ribosyl)ation of nuclear proteins in human fibroblasts.Condensation of nucleic acids by intercalating aromatic cations.Vosaroxin : a novel antineoplastic quinolone.RNA targeting by small molecules: Binding of protoberberine, benzophenanthridine and aristolochia alkaloids to various RNA structures.Fifty years of DNA "breathing": Reflections on old and new approaches.Luteolin, an emerging anti-cancer flavonoid, poisons eukaryotic DNA topoisomerase I.
P2860
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P2860
description
1981 nî lūn-bûn
@nan
1981年の論文
@ja
1981年学术文章
@wuu
1981年学术文章
@zh-cn
1981年学术文章
@zh-hans
1981年学术文章
@zh-my
1981年学术文章
@zh-sg
1981年學術文章
@yue
1981年學術文章
@zh
1981年學術文章
@zh-hant
name
DNA modification and cancer.
@en
type
label
DNA modification and cancer.
@en
prefLabel
DNA modification and cancer.
@en
P1476
DNA modification and cancer.
@en
P2093
P304
P356
10.1146/ANNUREV.BI.50.070181.001111
P577
1981-01-01T00:00:00Z