The extracellular matrix protein ITIH5 is a novel prognostic marker in invasive node-negative breast cancer and its aberrant expression is caused by promoter hypermethylation.
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Frequent loss of endothelin-3 (EDN3) expression due to epigenetic inactivation in human breast cancerSample prep for proteomics of breast cancer: proteomics and gene ontology reveal dramatic differences in protein solubilization preferences of radioimmunoprecipitation assay and urea lysis buffersPromoter hypermethylation of the SFRP2 gene is a high-frequent alteration and tumor-specific epigenetic marker in human breast cancerFrequent expression loss of Inter-alpha-trypsin inhibitor heavy chain (ITIH) genes in multiple human solid tumors: a systematic expression analysisRecent advances in the molecular diagnostics of gastric cancerGene expression profiling associated with the progression to poorly differentiated thyroid carcinomasNuclear detection of Y-box protein-1 (YB-1) closely associates with progesterone receptor negativity and is a strong adverse survival factor in human breast cancer.Enhancer of the rudimentary gene homologue (ERH) expression pattern in sporadic human breast cancer and normal breast tissue.Gene signatures in wound tissue as evidenced by molecular profiling in the chick embryo model.Epigenome remodelling in breast cancer: insights from an early in vitro model of carcinogenesisThe functional cancer map: a systems-level synopsis of genetic deregulation in cancerThe vasculome of the mouse brain.[Preliminary study of MALDI-TOF mass spectrometry-based screening of patients with the NSCLC serum-specific peptides].Identification of N-glycosylation in hepatocellular carcinoma patients' serum with a comparative proteomic approachEpigenetic regulation of Elf5 is associated with epithelial-mesenchymal transition in urothelial cancer.Aberrant DNA hypermethylation of the ITIH5 tumor suppressor gene in acute myeloid leukemia.Abundant NDRG2 Expression Is Associated with Aggressiveness and Unfavorable Patients' Outcome in Basal-Like Breast CancerOASIS/CREB3L1 is epigenetically silenced in human bladder cancer facilitating tumor cell spreading and migration in vitroGenome-wide in vivo RNAi screen identifies ITIH5 as a metastasis suppressor in pancreatic cancer.Low expression of ITIH5 in adenocarcinoma of the lung is associated with unfavorable patients' outcomePromoter hypermethylation of the tumor-suppressor genes ITIH5, DKK3, and RASSF1A as novel biomarkers for blood-based breast cancer screening.Tumor Necrosis Factor-stimulated Gene 6 (TSG-6)-mediated Interactions with the Inter-α-inhibitor Heavy Chain 5 Facilitate Tumor Growth Factor β1 (TGFβ1)-dependent Fibroblast to Myofibroblast DifferentiationITIH3 is a potential biomarker for early detection of gastric cancer.ITIH5 mediates epigenetic reprogramming of breast cancer cells.Epigenetic repression of regulator of G-protein signaling 2 by ubiquitin-like with PHD and ring-finger domain 1 promotes bladder cancer progression.Gene expression analysis combined with functional genomics approach identifies ITIH5 as tumor suppressor gene in cervical carcinogenesis.Epigenetic loss of putative tumor suppressor SFRP3 correlates with poor prognosis of lung adenocarcinoma patients.Nuclear transport receptor karyopherin-α2 promotes malignant breast cancer phenotypes in vitro.A urinary microRNA signature can predict the presence of bladder urothelial carcinoma in patients undergoing surveillance.Epigenetic inactivation of the novel candidate tumor suppressor gene ITIH5 in colon cancer predicts unfavorable overall survival in the CpG island methylator phenotype.β-cell-specific gene repression: a mechanism to protect against inappropriate or maladjusted insulin secretion?ITIH5 induces a shift in TGF-β superfamily signaling involving Endoglin and reduces risk for breast cancer metastasis and tumor death.The transfer of heavy chains from bikunin proteins to hyaluronan requires both TSG-6 and HC2.Candidate genes involving in tumorigenesis of cholangiocarcinoma induced by Opisthorchis viverrini infection.[Tumorigenesis from a pathological perspective : Tumor spread and epigenetically regulated genes in bladder cancer].Decreased ITIH5 expression is associated with poor prognosis in primary gastric cancer.ITIH-5 expression in human adipose tissue is increased in obesity.
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P2860
The extracellular matrix protein ITIH5 is a novel prognostic marker in invasive node-negative breast cancer and its aberrant expression is caused by promoter hypermethylation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
The extracellular matrix prote ...... by promoter hypermethylation.
@en
type
label
The extracellular matrix prote ...... by promoter hypermethylation.
@en
prefLabel
The extracellular matrix prote ...... by promoter hypermethylation.
@en
P2093
P2860
P356
P1433
P1476
The extracellular matrix prote ...... by promoter hypermethylation.
@en
P2093
Chorovicer M
Hartmann A
Knuechel R
Kristiansen G
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210669
P407
P50
P577
2007-07-23T00:00:00Z
P5875
P6179
1003891366