HMGB1 is an endogenous immune adjuvant released by necrotic cells. - Wikidata - wikimedia - TriplyDB

HMGB1 is an endogenous immune adjuvant released by necrotic cells.

HMGB1 is an endogenous immune adjuvant released by necrotic cells.

http://www.wikidata.org/entity/Q40104101

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Lectin of Concanavalin A as an anti-hepatoma therapeutic agent Linking innate and adaptive immunity: human Vgamma9Vdelta2 T cells enhance CD40 expression and HMGB-1 secretion Many stimuli pull the necrotic trigger, an overview Interleukin-1 stimulates beta-cell necrosis and release of the immunological adjuvant HMGB1 The implication and potential applications of high-mobility group box 1 protein in breast cancer Disruption of a Regulatory Network Consisting of Neutrophils and Platelets Fosters Persisting Inflammation in Rheumatic Diseases Vascular Remodelling and Mesenchymal Transition in Systemic Sclerosis A sequence-specific DNA binding small molecule triggers the release of immunogenic signals and phagocytosis in a model of B-cell lymphoma Prognostic and Predictive Value of DAMPs and DAMP-Associated Processes in Cancer High-mobility Group Box Protein-1, Matrix Metalloproteinases, and Vitamin D in Keloids and Hypertrophic Scars The role of HMGB1 in the pathogenesis of inflammatory and autoimmune diseases Cell death in the pathogenesis of immune-mediated diseases: the role of HMGB1 and DAMP-PAMP complexes The translocation of nuclear molecules during inflammation and cell death PAMPs and DAMPs as triggers for DIC Emerging roles for HMGB1 protein in immunity, inflammation, and cancer Antitumor immune responses mediated by dendritic cells: How signals derived from dying cancer cells drive antigen cross-presentation HMGB1 conveys immunosuppressive characteristics on regulatory and conventional T cells Drp1 stabilizes p53 on the mitochondria to trigger necrosis under oxidative stress conditions in vitro and in vivo HMGB1 loves company Oxidation of HMGB1 causes attenuation of its pro-inflammatory activity and occurs during liver ischemia and reperfusion How dying cells alert the immune system to danger Recent insights into the implications of metabolism in plasmacytoid dendritic cell innate functions: Potential ways to control these functions Alarmin IL-33 elicits potent TB-specific cell-mediated responses.DNA alkylating therapy induces tumor regression through an HMGB1-mediated activation of innate immunity The alarmin Mrp8/14 as regulator of the adaptive immune response during allergic contact dermatitis Apoptotic regulation of epithelial cellular extrusion Elevated plasma level of HMGB1 is associated with disease activity and combined alterations with IFN-α and TNF-α in systemic lupus erythematosus.Immune regulatory neural stem/precursor cells protect from central nervous system autoimmunity by restraining dendritic cell function Emerging role of HMGB1 in lung diseases: friend or foe.A proteolytic cascade controls lysosome rupture and necrotic cell death mediated by lysosome-destabilizing adjuvants.Antibacterial mechanism of high-mobility group nucleosomal-binding domain 2 on the Gram-negative bacteria Escherichia coli.Anti-HMGB1 neutralizing antibody ameliorates neutrophilic airway inflammation by suppressing dendritic cell-mediated Th17 polarization.Expression and effects of high-mobility group box 1 in cervical cancer.Inhibition of Drp1 hyper-activation is protective in animal models of experimental multiple sclerosis.D-K6L 9 peptide combination with IL-12 inhibits the recurrence of tumors in mice.Effects of single or combined treatments with radiation and chemotherapy on survival and danger signals expression in glioblastoma cell lines.The role of high mobility group box 1 in innate immunity.Programmed necrosis induced by asbestos in human mesothelial cells causes high-mobility group box 1 protein release and resultant inflammation.HMGB1 and cord blood: its role as immuno-adjuvant factor in innate immunity.Benign elevations in serum aminotransferases and biomarkers of hepatotoxicity in healthy volunteers treated with cholestyramine.

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HMGB1 is an endogenous immune adjuvant released by necrotic cells.

http://www.wikidata.org/entity/Q40104101

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2004 nî lūn-bûn

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2004年の論文

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年学术文章

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2004年學術文章

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2004年學術文章

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2004年學術文章

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name

HMGB1 is an endogenous immune adjuvant released by necrotic cells.

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type

label

HMGB1 is an endogenous immune adjuvant released by necrotic cells.

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prefLabel

HMGB1 is an endogenous immune adjuvant released by necrotic cells.

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SJ.EMBOR.7400205

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HMGB1 is an endogenous immune adjuvant released by necrotic cells.

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P2093

Angelo A Manfredi

http://www.w3.org/2001/XMLSchema#string

Annalisa Capobianco

http://www.w3.org/2001/XMLSchema#string

Barbara Valentinis

http://www.w3.org/2001/XMLSchema#string

Catia Traversari

http://www.w3.org/2001/XMLSchema#string

Federica Catalanotti

http://www.w3.org/2001/XMLSchema#string

Marta Giazzon

http://www.w3.org/2001/XMLSchema#string

Paola Scaffidi

http://www.w3.org/2001/XMLSchema#string

P2860

The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

Immunogenicity of apoptotic cells in vivo: role of antigen load, antigen-presenting cells, and cytokines

HMG-1 as a late mediator of endotoxin lethality in mice

HMGB1 as a DNA-binding cytokine

The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn mice

Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation

High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes

Molecular identification of a danger signal that alerts the immune system to dying cells

Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion.

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10.1038/SJ.EMBOR.7400205

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8

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5

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Marco E. Bianchi

Ingrid E Dumitriu

Susanne Müller

Matteo Iannacone

Patrizia Rovere-Querini

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2004-07-23T00:00:00Z

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8437978

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15272298

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1299116

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