Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans.
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Recent advances on Candida albicans biology and virulenceIncreased extracellular heat shock protein 90α in severe sepsis and SIRS associated with multiple organ failure and related to acute inflammatory-metabolic stress response in childrenThe global regulator Ncb2 escapes from the core promoter and impacts transcription in response to drug stress in Candida albicans.The Hsp90 Chaperone Network Modulates Candida Virulence Traits.The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation.Chaperone co-inducer BGP-15 inhibits histone deacetylases and enhances the heat shock response through increased chromatin accessibility.Ydj1 governs fungal morphogenesis and stress response, and facilitates mitochondrial protein import via Mas1 and Mas2.mTORC2/AKT/HSF1/HuR constitute a feed-forward loop regulating Rictor expression and tumor growth in glioblastoma.Stress Adaptation.Candida albicans Heat Shock Proteins and Hsps-Associated Signaling Pathways as Potential Antifungal Targets.The Candida albicans stress response gene Stomatin-Like Protein 3 is implicated in ROS-induced apoptotic-like death of yeast phase cells.Systematic identification and characterization of stress-inducible heat shock proteins (HSPs) in the salmon louse (Lepeophtheirus salmonis).Wor1 establishes opaque cell fate through inhibition of the general co-repressor Tup1 in Candida albicans.Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space.
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Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
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2016年學術文章
@zh-hant
name
Hsf1 and Hsp90 orchestrate tem ...... hitecture in Candida albicans.
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type
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Hsf1 and Hsp90 orchestrate tem ...... hitecture in Candida albicans.
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prefLabel
Hsf1 and Hsp90 orchestrate tem ...... hitecture in Candida albicans.
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Hsf1 and Hsp90 orchestrate tem ...... chitecture in Candida albicans
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P2093
Louise A Walker
Zhengqiang Miao
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10.1038/NCOMMS11704
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P577
2016-05-26T00:00:00Z