Premature termination codon readthrough in human cells occurs in novel cytoplasmic foci and requires UPF proteins.

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Optimized approach for the identification of highly efficient correctors of nonsense mutations in human diseases.

P2860

Q45423056-42973228-E623-4C28-8A31-39C2111E302C

P2860

Premature termination codon readthrough in human cells occurs in novel cytoplasmic foci and requires UPF proteins.

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http://www.wikidata.org/entity/Q40119962

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Premature termination codon re ...... oci and requires UPF proteins.

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Premature termination codon re ...... oci and requires UPF proteins.

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Premature termination codon re ...... oci and requires UPF proteins.

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P1476

Premature termination codon re ...... oci and requires UPF proteins.

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Catherine Leroy

http://www.w3.org/2001/XMLSchema#string

Dieter C Gruenert

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Elisabeth Werkmeister

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Sara Gonzalez-Hilarion

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P2860

Selective translational repression of truncated proteins from frameshift mutation-derived mRNAs in tumors

Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon

SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay

Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay

A role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies.

The human LSm1-7 proteins colocalize with the mRNA-degrading enzymes Dcp1/2 and Xrnl in distinct cytoplasmic foci.

Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures

Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4)

Cell mechanics and the cytoskeleton

Cytoplasmic foci are sites of mRNA decay in human cells

P304

3009-3022

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scholarly article

P356

10.1242/JCS.198176

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English

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P478

130

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P577

2017-07-25T00:00:00Z

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28743738

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P932

5612172

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Premature termination codon readthrough in human cells occurs in novel cytoplasmic foci and requires UPF proteins.

about

P2860

P2860

Premature termination codon readthrough in human cells occurs in novel cytoplasmic foci and requires UPF proteins.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932