Runx2 determines bone maturity and turnover rate in postnatal bone development and is involved in bone loss in estrogen deficiency.
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Repression of Runx2 by androgen receptor (AR) in osteoblasts and prostate cancer cells: AR binds Runx2 and abrogates its recruitment to DNAModulation of Runx2 activity by estrogen receptor-alpha: implications for osteoporosis and breast cancerFate decision of mesenchymal stem cells: adipocytes or osteoblasts?Osteoblasts Are the Centerpiece of the Metastatic Bone MicroenvironmentTyrosine kinase inhibitors and mesenchymal stromal cells: effects on self-renewal, commitment and functionsRegulation of adult bone turnover by sex steroidsSP7 inhibits osteoblast differentiation at a late stage in miceConcerted stimuli regulating osteo-chondral differentiation from stem cells: phenotype acquisition regulated by microRNAs.Expression analysis of genes associated with human osteosarcoma tumors shows correlation of RUNX2 overexpression with poor response to chemotherapy.Generation of functional mesenchymal stem cells from different induced pluripotent stem cell lines.Effects of altered CXCL12/CXCR4 axis on BMP2/Smad/Runx2/Osterix axis and osteogenic gene expressions during osteogenic differentiation of MSCs.The gene for aromatase, a rate-limiting enzyme for local estrogen biosynthesis, is a downstream target gene of Runx2 in skeletal tissues.Dual roles of smad proteins in the conversion from myoblasts to osteoblastic cells by bone morphogenetic proteins.Overexpression of Bcl2 in osteoblasts inhibits osteoblast differentiation and induces osteocyte apoptosis.Looping mediated interaction between the promoter and 3' UTR regulates type II collagen expression in chondrocytes.Kruppel-like factor 4 attenuates osteoblast formation, function, and cross talk with osteoclastsThe Role of RUNX2 in Osteosarcoma Oncogenesis.Sex steroid actions in male boneModulation of the osteosarcoma expression phenotype by microRNAsFocal adhesions in osteoneogenesisRunx2 activity in committed osteoblasts is not essential for embryonic skeletogenesis.Loss of Runx2 in committed osteoblasts impairs postnatal skeletogenesis.The Sox2 high mobility group transcription factor inhibits mature osteoblast function in transgenic miceEstrogens antagonize RUNX2-mediated osteoblast-driven osteoclastogenesis through regulating RANKL membrane association.Runx2 protein expression utilizes the Runx2 P1 promoter to establish osteoprogenitor cell number for normal bone formationRole of tartrate-resistant acid phosphatase (TRAP) in long bone developmentDspp mutations disrupt mineralization homeostasis during odontoblast differentiation.Effect of microgrooves and fibronectin conjugation on the osteoblast marker gene expression and differentiation.Metaphyseal dysplasia with maxillary hypoplasia and brachydactyly is caused by a duplication in RUNX2.The Role of KV7.3 in Regulating Osteoblast Maturation and MineralizationTranscription factors Runx1 to 3 are expressed in the lacrimal gland epithelium and are involved in regulation of gland morphogenesis and regeneration.Coordinated transcriptional regulation of bone homeostasis by Ebf1 and Zfp521 in both mesenchymal and hematopoietic lineages.Expression of Runx2 transcription factor in non-skeletal tissues, sperm and brain.Zfp521 antagonizes Runx2, delays osteoblast differentiation in vitro, and promotes bone formation in vivo.Inducible expression of Runx2 results in multiorgan abnormalities in mice.The RUNX family in breast cancer: relationships with estrogen signaling.RUNX2 in mammary gland development and breast cancer.Runx2 promotes both osteoblastogenesis and novel osteoclastogenic signals in ST2 mesenchymal progenitor cells.Role of Slug transcription factor in human mesenchymal stem cells.Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis.
P2860
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P2860
Runx2 determines bone maturity and turnover rate in postnatal bone development and is involved in bone loss in estrogen deficiency.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Runx2 determines bone maturity ...... e loss in estrogen deficiency.
@en
type
label
Runx2 determines bone maturity ...... e loss in estrogen deficiency.
@en
prefLabel
Runx2 determines bone maturity ...... e loss in estrogen deficiency.
@en
P2093
P356
P1476
Runx2 determines bone maturity ...... e loss in estrogen deficiency.
@en
P2093
Carolina A Yoshida
Hideki Kitaura
Hiroshi Kawaguchi
Kei Yamana
Kouhei Nakamura
Kozo Nakamura
Masako Ito
Naoko Kanatani
Norio Amizuka
Ryo Fukuyama
P304
P356
10.1002/DVDY.21187
P577
2007-07-01T00:00:00Z