The hinge region regulates DNA binding, nuclear translocation, and transactivation of the androgen receptor.
about
A sting in the tail: the N-terminal domain of the androgen receptor as a drug targetExpression of Tubb3, a beta-tubulin isotype, is regulated by androgens in mouse and rat Sertoli cellsSUMO-specific protease 1 (SENP1) reverses the hormone-augmented SUMOylation of androgen receptor and modulates gene responses in prostate cancer cells.Androgens and the male reproductive tract: an overview of classical roles and current perspectives.Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant.Androgen receptor splice variants determine taxane sensitivity in prostate cancer.Minireview: The versatile roles of lysine deacetylases in steroid receptor signalingComparing the rules of engagement of androgen and glucocorticoid receptorsThe progesterone receptor hinge region regulates the kinetics of transcriptional responses through acetylation, phosphorylation, and nuclear retention.Phosphorylation of the mutant K303R estrogen receptor alpha at serine 305 affects aromatase inhibitor sensitivityEstrogen receptor mutations and changes in downstream gene expression and signalingBiological properties of androgen receptor pure antagonist for treatment of castration-resistant prostate cancer: optimization from lead compound to CH5137291.The impact of point mutations in the human androgen receptor: classification of mutations on the basis of transcriptional activityAcetylation-mediated epigenetic regulation of glucocorticoid receptor activity: circadian rhythm-associated alterations of glucocorticoid actions in target tissuesEvidence on how a conserved glycine in the hinge region of HapR regulates its DNA binding ability: lessons from a natural variantChallenges in clinical and laboratory diagnosis of androgen insensitivity syndrome: a case reportStructural and functional analysis of domains of the progesterone receptor.Androgen receptor splice variants activate androgen receptor target genes and support aberrant prostate cancer cell growth independent of canonical androgen receptor nuclear localization signal.Androgen receptor: structure, role in prostate cancer and drug discovery.Regulatory function of the P295-T311 motif of the estrogen receptor alpha - does proteasomal degradation of the receptor induce emergence of peptides implicated in estrogenic responses?Functional mimicry of the acetylated C-terminal tail of p53 by a SUMO-1 acetylated domain, SADHDAC inhibition impedes epithelial-mesenchymal plasticity and suppresses metastatic, castration-resistant prostate cancer.A novel androgen receptor amino terminal region reveals two classes of amino/carboxyl interaction-deficient variants with divergent capacity to activate responsive sites in chromatin.Diverse roles of androgen receptor (AR) domains in AR-mediated signaling.B2 attenuates polyglutamine-expanded androgen receptor toxicity in cell and fly models of spinal and bulbar muscular atrophy.The role of androgen receptor mutations in prostate cancer progression.Structure of the homodimeric androgen receptor ligand-binding domainPC-1 works in conjunction with E3 ligase CHIP to regulate androgen receptor stability and activity.The androgen/androgen receptor axis in prostate cancer.Hepatocyte nuclear factor-4α, a multifunctional nuclear receptor associated with cardiovascular disease and cholesterol catabolism.Proline-Directed Androgen Receptor Phosphorylation.Polyglutamine androgen receptor-mediated neuromuscular disease.Allosteric conversation in the androgen receptor ligand-binding domain surfaces.Analysis of interdomain interactions of the androgen receptor.Regulation of the androgen receptor by SET9-mediated methylation.The rules of DNA recognition by the androgen receptor.Influence of nucleophosmin/B23 on DNA binding and transcriptional activity of the androgen receptor in prostate cancer cell.Targeting the BAF57 SWI/SNF subunit in prostate cancer: a novel platform to control androgen receptor activity.Lysine acetyltransferases cyclic adenosine monophosphate response element-binding binding protein and acetyltransferase p300 attenuate transcriptional activity of the mineralocorticoid receptor through its acetylation.Androgen receptor signalling in prostate cancer: the functional consequences of acetylation
P2860
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P2860
The hinge region regulates DNA binding, nuclear translocation, and transactivation of the androgen receptor.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The hinge region regulates DNA ...... tion of the androgen receptor.
@en
type
label
The hinge region regulates DNA ...... tion of the androgen receptor.
@en
prefLabel
The hinge region regulates DNA ...... tion of the androgen receptor.
@en
P2093
P1433
P1476
The hinge region regulates DNA ...... tion of the androgen receptor.
@en
P2093
Annemie Haelens
Leen Callewaert
Sarah Denayer
Tamzin Tanner
P304
P356
10.1158/0008-5472.CAN-06-1701
P407
P577
2007-05-01T00:00:00Z