The p110alpha isoform of phosphatidylinositol 3-kinase is essential for polyomavirus middle T antigen-mediated transformation.
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Should individual PI3 kinase isoforms be targeted in cancer?SIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasisAdapting the Stress Response: Viral Subversion of the mTOR Signaling PathwayComputer-aided targeting of the PI3K/Akt/mTOR pathway: toxicity reduction and therapeutic opportunitiesTargeting the phosphoinositide 3-kinase pathway in cancerA Transformation-Defective Polyomavirus Middle T Antigen with a Novel Defect in PI3 Kinase Signaling.Phosphatidylinositol 3-kinase: the oncoprotein.The phosphatidylinositol 3-kinase (PI3K) isoform dependence of tumor formation is determined by the genetic mode of PI3K pathway activation rather than by tissue type.Transgenic expression of polyomavirus middle T antigen in the mouse prostate gives rise to carcinoma.Cellular transformation by Simian Virus 40 and Murine Polyoma Virus T antigens.Lessons in signaling and tumorigenesis from polyomavirus middle T antigen.RelA-Induced Interferon Response Negatively Regulates ProliferationAlterations of EGFR, p53 and PTEN that mimic changes found in basal-like breast cancer promote transformation of human mammary epithelial cells.The TORrid affairs of viruses: effects of mammalian DNA viruses on the PI3K-Akt-mTOR signalling pathway.Lessons from polyoma middle T antigen on signaling and transformation: A DNA tumor virus contribution to the war on cancer.Inducible and coupled expression of the polyomavirus middle T antigen and Cre recombinase in transgenic mice: an in vivo model for synthetic viability in mammary tumour progression.Polyomavirus middle T antigen induces the transcription of osteopontin, a gene important for the migration of transformed cells.Transformation by Polyomavirus Middle T Antigen Involves a Unique Bimodal Interaction with the Hippo Effector YAP.
P2860
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P2860
The p110alpha isoform of phosphatidylinositol 3-kinase is essential for polyomavirus middle T antigen-mediated transformation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The p110alpha isoform of phosp ...... tigen-mediated transformation.
@en
type
label
The p110alpha isoform of phosp ...... tigen-mediated transformation.
@en
prefLabel
The p110alpha isoform of phosp ...... tigen-mediated transformation.
@en
P2093
P2860
P356
P1433
P1476
The p110alpha isoform of phosp ...... tigen-mediated transformation.
@en
P2093
Brian S Schaffhausen
Jean J Zhao
Tamara Utermark
Thomas M Roberts
P2860
P304
P356
10.1128/JVI.00115-07
P407
P577
2007-04-18T00:00:00Z