The human breast cancer resistance protein (BCRP/ABCG2) shows conformational changes with mitoxantrone.
about
The multidrug transporter ABCG2: still more questions than answersDetergent screening and purification of the human liver ABC transporters BSEP (ABCB11) and MDR3 (ABCB4) expressed in the yeast Pichia pastorisJump into a New Fold-A Homology Based Model for the ABCG2/BCRP Multidrug TransporterDeterminants of the activity and substrate recognition of breast cancer resistance protein (ABCG2).Transmembrane helices 1 and 6 of the human breast cancer resistance protein (BCRP/ABCG2): identification of polar residues important for drug transport.ARRY-334543 reverses multidrug resistance by antagonizing the activity of ATP-binding cassette subfamily G member 2.Identification of proline residues in or near the transmembrane helices of the human breast cancer resistance protein (BCRP/ABCG2) that are important for transport activity and substrate specificity.Structural determinants of peripheral O-arylcarbamate FAAH inhibitors render them dual substrates for Abcb1 and Abcg2 and restrict their access to the brainStructure and function of the human breast cancer resistance protein (BCRP/ABCG2).Predicting substrates of the human breast cancer resistance protein using a support vector machine method.Role of the breast cancer resistance protein (BCRP/ABCG2) in drug transport--an update.Three-dimensional structure of the human breast cancer resistance protein (BCRP/ABCG2) in an inward-facing conformation.Nilotinib potentiates anticancer drug sensitivity in murine ABCB1-, ABCG2-, and ABCC10-multidrug resistance xenograft modelsA new strategy to rapidly evaluate kinetics of glucuronide efflux by breast cancer resistance protein (BCRP/ABCG2).Drug transport by breast cancer resistance protein.The ABCG family of membrane-associated transporters: you don't have to be big to be mightyHuman ABCG2: structure, function, and its role in multidrug resistance.Human ABC transporter ABCG2/BCRP expression in chemoresistance: basic and clinical perspectives for molecular cancer therapeutics.Structure and function of BCRP, a broad specificity transporter of xenobiotics and endobiotics.Overcoming multidrug resistance with nanomedicines.Telatinib reverses chemotherapeutic multidrug resistance mediated by ABCG2 efflux transporter in vitro and in vivoThe Transmission Interfaces Contribute Asymmetrically to the Assembly and Activity of Human P-glycoproteinEfflux proteins at the blood-brain barrier: review and bioinformatics analysis.GW583340 and GW2974, human EGFR and HER-2 inhibitors, reverse ABCG2- and ABCB1-mediated drug resistance.The human transporter associated with antigen processing: molecular models to describe peptide binding competent states.Comparison of intestinal absorption and disposition of structurally similar bioactive flavones in Radix Scutellariae.Identification of residues in ABCG2 affecting protein trafficking and drug transport, using co-evolutionary analysis of ABCG sequences.The structure of the human ABC transporter ABCG2 reveals a novel mechanism for drug extrusion.Recombinant synthesis of human ABCG2 expressed in the yeast Saccharomyces cerevisiae: an experimental methodological study.Quizartinib (AC220) reverses ABCG2-mediated multidrug resistance: In vitro and in vivo studies.Residues contributing to drug transport by ABCG2 are localised to multiple drug-binding pockets.Pharmacogenetic Aspects of the Interaction of AT1 Receptor Antagonists With ATP-Binding Cassette Transporter ABCG2.
P2860
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P2860
The human breast cancer resistance protein (BCRP/ABCG2) shows conformational changes with mitoxantrone.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
The human breast cancer resist ...... nal changes with mitoxantrone.
@en
type
label
The human breast cancer resist ...... nal changes with mitoxantrone.
@en
prefLabel
The human breast cancer resist ...... nal changes with mitoxantrone.
@en
P2093
P2860
P1433
P1476
The human breast cancer resist ...... nal changes with mitoxantrone.
@en
P2093
Janice Chan
Mark F Rosenberg
Qingcheng Mao
Robert C Ford
Xiaokun Cai
Xiaoping Liu
Zhanglin Ni
Zsolt Bikadi
P2860
P304
P356
10.1016/J.STR.2010.01.017
P577
2010-03-01T00:00:00Z