BRCA1 haploinsufficiency, but not heterozygosity for a BRCA1-truncating mutation, deregulates homologous recombination.
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53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaksControversial BRCA1 allelotypes in commonly used breast cancer cell linesWild-type BRCA1, but not mutated BRCA1, regulates the expression of the nuclear form of beta-cateninEMSY overexpression disrupts the BRCA2/RAD51 pathway in the DNA-damage response: implications for chromosomal instability/recombination syndromes as checkpoint diseases.Estrogen receptor positive breast cancers in BRCA1 mutation carriers: clinical risk factors and pathologic featuresPoly(ADP-Ribose) polymerase inhibition: "targeted" therapy for triple-negative breast cancer.Mechanisms of increased risk of tumorigenesis in Atm and Brca1 double heterozygosity.Cordycepin blocks lung injury-associated inflammation and promotes BRCA1-deficient breast cancer cell killing by effectively inhibiting PARP.BRCA1-hapoinsufficiency: Unraveling the molecular and cellular basis for tissue-specific cancerGermline BRCA1 mutation reprograms breast epithelial cell metabolism towards mitochondrial-dependent biosynthesis: evidence for metformin-based "starvation" strategies in BRCA1 carriers.Prevalence and clinical significance of BRCA1/2 germline and somatic mutations in Taiwanese patients with ovarian cancer.BRCA1 16 years later: risk-associated BRCA1 mutations and their functional implications.DNA repair capacity is impaired in healthy BRCA1 heterozygous mutation carriers.Ionizing radiation or mitomycin-induced micronuclei in lymphocytes of BRCA1 or BRCA2 mutation carriers.Germline copy number variations in BRCA1-associated ovarian cancer patients.
P2860
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P2860
BRCA1 haploinsufficiency, but not heterozygosity for a BRCA1-truncating mutation, deregulates homologous recombination.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
BRCA1 haploinsufficiency, but ...... ates homologous recombination.
@en
type
label
BRCA1 haploinsufficiency, but ...... ates homologous recombination.
@en
prefLabel
BRCA1 haploinsufficiency, but ...... ates homologous recombination.
@en
P356
P1433
P1476
BRCA1 haploinsufficiency, but ...... ates homologous recombination.
@en
P2093
Abdellah Belmaaza
Isabelle Cousineau
P304
P356
10.4161/CC.6.8.4105
P577
2007-04-02T00:00:00Z