Pyrophosphate inhibits mineralization of osteoblast cultures by binding to mineral, up-regulating osteopontin, and inhibiting alkaline phosphatase activity.
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The enamel protein amelotin is a promoter of hydroxyapatite mineralizationA novel IFITM5 mutation in severe atypical osteogenesis imperfecta type VI impairs osteoblast production of pigment epithelium-derived factorHeparanase expression and activity influences chondrogenic and osteogenic processes during endochondral bone formationPathophysiology of hypophosphatasia and the potential role of asfotase alfaPhosphate/pyrophosphate and MV-related proteins in mineralisation: discoveries from mouse modelsExtracellular matrix mineralization in periodontal tissues: Noncollagenous matrix proteins, enzymes, and relationship to hypophosphatasia and X-linked hypophosphatemiaThe role of fetuin-A in mineral trafficking and depositionExcessive Osteocytic Fgf23 Secretion Contributes to Pyrophosphate Accumulation and Mineralization Defect in Hyp MiceENPP1-Fc prevents mortality and vascular calcifications in rodent model of generalized arterial calcification of infancyMolecular Basis of Purinergic Signal Metabolism by Ectonucleotide Pyrophosphatase/Phosphodiesterases 4 and 1 and Implications in StrokeDemineralization-remineralization dynamics in teeth and boneEffects of Different Variants in the ENPP1 Gene on the Functional Properties of Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 1Proteolytic processing of osteopontin by PHEX and accumulation of osteopontin fragments in Hyp mouse bone, the murine model of X-linked hypophosphatemiaLoss of skeletal mineralization by the simultaneous ablation of PHOSPHO1 and alkaline phosphatase function: a unified model of the mechanisms of initiation of skeletal calcificationThe Phosphate Source Influences Gene Expression and Quality of Mineralization during In Vitro Osteogenic Differentiation of Human Mesenchymal Stem CellsMEPE is a novel regulator of growth plate cartilage mineralizationTooth root dentin mineralization defects in a mouse model of hypophosphatasia.Phosphate induces formation of matrix vesicles during odontoblast-initiated mineralization in vitroDiscovery and validation of a series of aryl sulfonamides as selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP).Chronic mineral dysregulation promotes vascular smooth muscle cell adaptation and extracellular matrix calcification.The inorganic pyrophosphate transporter ANK preserves the differentiated phenotype of articular chondrocyte.Coordinated gene expression during gilthead sea bream skeletogenesis and its disruption by nutritional hypervitaminosis AComparative in vitro study regarding the biocompatibility of titanium-base composites infiltrated with hydroxyapatite or silicatitanateAsfotase-α improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1.Tissue-nonspecific alkaline phosphatase deficiency causes abnormal craniofacial bone development in the Alpl(-/-) mouse model of infantile hypophosphatasiaAltered bone development and an increase in FGF-23 expression in Enpp1(-/-) mice.Dual role of the Trps1 transcription factor in dentin mineralization.Central role of pyrophosphate in acellular cementum formation.miR-214 targets ATF4 to inhibit bone formation.Optimisation of the differing conditions required for bone formation in vitro by primary osteoblasts from mice and rats.Runx2 haploinsufficiency ameliorates the development of ossification of the posterior longitudinal ligament.Abnormal osteopontin and matrix extracellular phosphoglycoprotein localization, and odontoblast differentiation, in X-linked hypophosphatemic teeth.Molecular, phenotypic aspects and therapeutic horizons of rare genetic bone disorders.Enpp1: a potential facilitator of breast cancer bone metastasis.Extracellular ATP released by osteoblasts is a key local inhibitor of bone mineralisation.The impairment of osteogenesis in bone sialoprotein (BSP) knockout calvaria cell cultures is cell density dependent.TNF-alpha promotes an odontoblastic phenotype in dental pulp cells.Enzyme replacement therapy prevents dental defects in a model of hypophosphatasia.Progressive ankylosis protein (ANK) in osteoblasts and osteoclasts controls bone formation and bone remodeling.Npp1 promotes atherosclerosis in ApoE knockout mice
P2860
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P2860
Pyrophosphate inhibits mineralization of osteoblast cultures by binding to mineral, up-regulating osteopontin, and inhibiting alkaline phosphatase activity.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Pyrophosphate inhibits mineral ...... alkaline phosphatase activity.
@en
type
label
Pyrophosphate inhibits mineral ...... alkaline phosphatase activity.
@en
prefLabel
Pyrophosphate inhibits mineral ...... alkaline phosphatase activity.
@en
P2093
P2860
P356
P1476
Pyrophosphate inhibits mineral ...... alkaline phosphatase activity.
@en
P2093
Esben S Sørensen
Fereshteh Azari
Marc D McKee
Mari T Kaartinen
William N Addison
P2860
P304
15872-15883
P356
10.1074/JBC.M701116200
P407
P577
2007-03-23T00:00:00Z