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Therapeutic CD154 antibody for lupus: promise for the future?

Therapeutic CD154 antibody for lupus: promise for the future?

http://www.wikidata.org/entity/Q40156609

about

The CD40/CD40L costimulatory pathway in inflammatory bowel disease Human immunoglobulin selection associated with class switch and possible tolerogenic origins for C delta class-switched B cells.Abnormal high-expression of CD154 on T lymphocytes of ankylosing spondylitis patients is down-regulated by etanercept treatment.Protective Role of Myeloid Cells Expressing a G-CSF Receptor Polymorphism in an Induced Model of Lupus.

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Therapeutic CD154 antibody for lupus: promise for the future?

http://www.wikidata.org/entity/Q40156609

description

2003 nî lūn-bûn

@nan

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

2003年论文

@zh

2003年论文

@zh-cn

name

Therapeutic CD154 antibody for lupus: promise for the future?

@en

type

label

Therapeutic CD154 antibody for lupus: promise for the future?

@en

prefLabel

Therapeutic CD154 antibody for lupus: promise for the future?

@en

P1433

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Journal of Clinical Investigation

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Therapeutic CD154 antibody for lupus: promise for the future?

@en

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Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

Revising B cell receptors

Germinal centers without T cells

Virus-induced maturation and activation of autoreactive memory B cells.

Abnormal germinal center reactions in systemic lupus erythematosus demonstrated by blockade of CD154-CD40 interactions.

Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production.

Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease. The salivary glands of patients with Sjögren's syndrome

Life and death in germinal centers (redux).

Immune regulation by CD40 and its ligand GP39.

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1480-1482

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scholarly article

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10.1172/JCI200320371

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P433

10

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112

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P577

2003-11-01T00:00:00Z

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14617748

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259140

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