Specific targeting of TGF-β family ligands demonstrates distinct roles in the regulation of muscle mass in health and disease.
about
Targeting TGF-β Mediated SMAD Signaling for the Prevention of Fibrosis.Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy.SMAD6 overexpression leads to accelerated myogenic differentiation of LMNA mutated cells.Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone
P2860
Specific targeting of TGF-β family ligands demonstrates distinct roles in the regulation of muscle mass in health and disease.
description
2017 nî lūn-bûn
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2017年の論文
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年學術文章
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2017年學術文章
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2017年學術文章
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name
Specific targeting of TGF-β fa ...... le mass in health and disease.
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type
label
Specific targeting of TGF-β fa ...... le mass in health and disease.
@en
prefLabel
Specific targeting of TGF-β fa ...... le mass in health and disease.
@en
P2093
P2860
P50
P356
P1476
Specific targeting of TGF-β fa ...... le mass in health and disease.
@en
P2093
Justin L Chen
Katharine Johnson
Kelly L Walton
Timothy D Colgan
P2860
P304
E5266-E5275
P356
10.1073/PNAS.1620013114
P407
P577
2017-06-12T00:00:00Z