The MDM2 ubiquitination signal in the DNA-binding domain of p53 forms a docking site for calcium calmodulin kinase superfamily members.
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Resistance and gain-of-resistance phenotypes in cancers harboring wild-type p53Cellular and molecular biology of aging endothelial cellsRoles of Chk1 in cell biology and cancer therapyDAPK-1 binding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing.A novel p53 phosphorylation site within the MDM2 ubiquitination signal: I. phosphorylation at SER269 in vivo is linked to inactivation of p53 function.Cooperative functions of Chk1 and Chk2 reduce tumour susceptibility in vivoA novel p53 phosphorylation site within the MDM2 ubiquitination signal: II. a model in which phosphorylation at SER269 induces a mutant conformation to p53Death-associated protein kinase 1 promotes growth of p53-mutant cancers.Hypermethylation of DAPK1 is an independent prognostic factor predicting survival in diffuse large B-cell lymphoma.A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk1.CYP1B1 promotes tumorigenesis via altered expression of CDC20 and DAPK1 genes in renal cell carcinoma.Oncogenic miR-17/20a Forms a Positive Feed-forward Loop with the p53 Kinase DAPK3 to Promote TumorigenesismiRNA-26b Overexpression in Ulcerative Colitis-associated Carcinogenesis.The DAP-kinase interactome.DAPK1 Signaling Pathways in Stroke: from Mechanisms to Therapies5-Fluorouracil signaling through a calcium-calmodulin-dependent pathway is required for p53 activation and apoptosis in colon carcinoma cells.Simian virus 40 activates ATR-Delta p53 signaling to override cell cycle and DNA replication control.DeltaNp63 transcriptionally regulates ATM to control p53 Serine-15 phosphorylation.The regulation of p53 by phosphorylation: a model for how distinct signals integrate into the p53 pathway.A central role for CK1 in catalyzing phosphorylation of the p53 transactivation domain at serine 20 after HHV-6B viral infection.Regulation of the E3 ubiquitin ligase activity of MDM2 by an N-terminal pseudo-substrate motif.Identification of two reactive cysteine residues in the tumor suppressor protein p53 using top-down FTICR mass spectrometry.
P2860
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P2860
The MDM2 ubiquitination signal in the DNA-binding domain of p53 forms a docking site for calcium calmodulin kinase superfamily members.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
The MDM2 ubiquitination signal ...... in kinase superfamily members.
@en
type
label
The MDM2 ubiquitination signal ...... in kinase superfamily members.
@en
prefLabel
The MDM2 ubiquitination signal ...... in kinase superfamily members.
@en
P2093
P2860
P356
P1476
The MDM2 ubiquitination signal ...... in kinase superfamily members.
@en
P2093
Ashley L Craig
Ben J Harrison
Irena Dornreiter
Jennifer A Chrystal
Jennifer A Fraser
Mary T Scott
Nathalie Sphyris
Ted R Hupp
P2860
P304
P356
10.1128/MCB.01595-06
P407
P577
2007-03-05T00:00:00Z