Protection of mice against lethal endotoxemia by a lipid A precursor.
about
Induction of early gene expression in murine macrophages by synthetic lipid A analogs with differing endotoxic potentials.Modulation of lipopolysaccharide-induced macrophage gene expression by Rhodobacter sphaeroides lipid A and SDZ 880.431Nuclear translocation of NF-kappaB in lipopolysaccharide-treated macrophages fails to correspond to endotoxicity: evidence suggesting a requirement for a gamma interferon-like signal.Calcineurin inactivation leads to decreased responsiveness to LPS in macrophages and dendritic cells and protects against LPS-induced toxicity in vivoDiphosphoryl lipid A from Rhodopseudomonas sphaeroides ATCC 17023 blocks induction of cachectin in macrophages by lipopolysaccharide.Macrophage activation by an ornithine-containing lipid or a serine-containing lipidEffects of pretreatment with SDZ MRL 953, a novel immunostimulatory lipid A analog, on endotoxin-induced acute lung injury in guinea pigs.Elimination and tissue distribution of the monosaccharide lipid A precursor, lipid X, in mice and sheep.A novel synthetic lipid A analog with low endotoxicity, DT-5461, prevents lethal endotoxemiaInhibition of endotoxin-induced priming of human neutrophils by lipid X and 3-Aza-lipid X.Free hydroxyl groups are not required for endotoxic activity of lipid A.Molecular adjuvants and immunomodulators: new approaches to immunization.Bacterial modulins: a novel class of virulence factors which cause host tissue pathology by inducing cytokine synthesisDetoxified exoantigens and phosphatidylinositol derivatives inhibit tumor necrosis factor induction by malarial exoantigens.In vivo inhibition of lipopolysaccharide-induced lethality and tumor necrosis factor synthesis by Rhodobacter sphaeroides diphosphoryl lipid A is dependent on corticosterone inductionDiphosphoryl lipid A obtained from the nontoxic lipopolysaccharide of Rhodopseudomonas sphaeroides is an endotoxin antagonist in miceImmunostimulatory, but not antiendotoxin, activity of lipid X is due to small amounts of contaminating N,O-acylated disaccharide-1-phosphate: in vitro and in vivo reevaluation of the biological activity of synthetic lipid XProtection of mice from lethal endotoxemia by use of an ornithine-containing lipid or a serine-containing lipid.Lipid X protects mice against fatal Escherichia coli infection.Lipid X ameliorates pulmonary hypertension and protects sheep from death due to endotoxin.Suppression of murine endotoxin response by E5531, a novel synthetic lipid A antagonist.Diphosphoryl lipid A derived from lipopolysaccharide (LPS) of Rhodopseudomonas sphaeroides inhibits activation of 70Z/3 cells by LPS.Optimal induction of tumor necrosis factor production in human monocytes requires complete S-form lipopolysaccharide.E5531, a synthetic non-toxic lipid A derivative blocks the immunobiological activities of lipopolysaccharideLipid IVA inhibits synthesis and release of tumor necrosis factor induced by lipopolysaccharide in human whole blood ex vivo.
P2860
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P2860
Protection of mice against lethal endotoxemia by a lipid A precursor.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Protection of mice against lethal endotoxemia by a lipid A precursor.
@en
type
label
Protection of mice against lethal endotoxemia by a lipid A precursor.
@en
prefLabel
Protection of mice against lethal endotoxemia by a lipid A precursor.
@en
P2093
P2860
P1476
Protection of mice against lethal endotoxemia by a lipid A precursor.
@en
P2093
P2860
P304
P407
P577
1986-06-01T00:00:00Z