FGFR3 intracellular mutations induce tyrosine phosphorylation in the Golgi and defective glycosylation.
about
New insight on FGFR3-related chondrodysplasias molecular physiopathology revealed by human chondrocyte gene expression profilingM-COPA suppresses endolysosomal Kit-Akt oncogenic signalling through inhibiting the secretory pathway in neoplastic mast cells.Tyrosine kinase inhibitor NVP-BGJ398 functionally improves FGFR3-related dwarfism in mouse model.Achondroplasia: Development, pathogenesis, and therapy.Mutant fibroblast growth factor receptor 3 induces intracellular signaling and cellular transformation in a cell type- and mutation-specific manner.The alternative TrkAIII splice variant targets the centrosome and promotes genetic instability.Oncogenic signaling by Kit tyrosine kinase occurs selectively on the Golgi apparatus in gastrointestinal stromal tumors.Effects of endoplasmic reticulum stressors on maturation and signaling of hemizygous and heterozygous wild-type and mutant forms of KIT.Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia.
P2860
Q33515573-F1E5F222-4B4A-4ED0-BC4F-914935E5DD8BQ36344903-A06F7125-0B42-48C0-B552-7DBEB9BD3298Q36867279-295C5249-F110-4C56-92FE-47519BC3B4E8Q39041957-298C3FC8-9652-4F0E-9D2B-3B7FC1ADD87EQ39800120-0129F366-0649-4339-9B26-33A5C6AE36B1Q39831330-82C63FCE-B69D-49F1-A254-D6840819DC29Q40956192-18AB4B81-607F-4342-8AE1-892669186016Q41134667-063B61D5-8139-44FF-AB8D-F7B32A2C94C4Q50080868-A166BCC0-7C5E-438F-8E65-6BC96653B3A7
P2860
FGFR3 intracellular mutations induce tyrosine phosphorylation in the Golgi and defective glycosylation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
FGFR3 intracellular mutations ...... i and defective glycosylation.
@en
type
label
FGFR3 intracellular mutations ...... i and defective glycosylation.
@en
prefLabel
FGFR3 intracellular mutations ...... i and defective glycosylation.
@en
P1476
FGFR3 intracellular mutations ...... i and defective glycosylation.
@en
P2093
Linda Gibbs
P304
P356
10.1016/J.BBAMCR.2006.12.010
P577
2007-01-20T00:00:00Z