Beta-arrestin and Mdm2 mediate IGF-1 receptor-stimulated ERK activation and cell cycle progression.
about
Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advancesIdentification of the cathelicidin peptide LL-37 as agonist for the type I insulin-like growth factor receptorβ-arrestin1 mediates metastatic growth of breast cancer cells by facilitating HIF-1-dependent VEGF expressionβ-Arrestin2 regulates lysophosphatidic acid-induced human breast tumor cell migration and invasion via Rap1 and IQGAP1Beta-arrestins: multifunctional cellular mediatorsTargeting of beta-arrestin2 to the centrosome and primary cilium: role in cell proliferation controlIndependent beta-arrestin2 and Gq/protein kinase Czeta pathways for ERK stimulated by angiotensin type 1A receptors in vascular smooth muscle cells converge on transactivation of the epidermal growth factor receptorRole of ubiquitination in IGF-1 receptor signaling and degradation.Non-visual arrestins are constitutively associated with the centrosome and regulate centrosome function.IGF-1 induces expression of zinc-finger protein 143 in colon cancer cells through phosphatidylinositide 3-kinase and reactive oxygen species.Something old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulationInsulin-like growth factor-I E-peptide activity is dependent on the IGF-I receptor.Antitumor effects and molecular mechanisms of figitumumab, a humanized monoclonal antibody to IGF-1 receptor, in esophageal carcinoma.Ligand-mediated endocytosis and trafficking of the insulin-like growth factor receptor I and insulin receptor modulate receptor function.Stromal expression of β-arrestin-1 predicts clinical outcome and tamoxifen response in breast cancer.Intact MDM2 E3 ligase activity is required for the cytosolic localization and function of β-arrestin2Differential protein expression profiles in estrogen receptor-positive and -negative breast cancer tissues using label-free quantitative proteomics.Insulin/Insulin-like growth factors in cancer: new roles for the aryl hydrocarbon receptor, tumor resistance mechanisms, and new blocking strategies.OVA66 increases cell growth, invasion and survival via regulation of IGF-1R-MAPK signaling in human cancer cells.Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signalingMechanisms underlying acute protection from cardiac ischemia-reperfusion injuryArrestin development: emerging roles for beta-arrestins in developmental signaling pathwaysInhibition of EGF-induced ERK/MAP kinase-mediated astrocyte proliferation by mu opioids: integration of G protein and beta-arrestin 2-dependent pathways.Lewis y regulate cell cycle related factors in ovarian carcinoma cell RMG-I in vitro via ERK and Akt signaling pathways.Engagement of β-arrestin by transactivated insulin-like growth factor receptor is needed for V2 vasopressin receptor-stimulated ERK1/2 activation.Selective recruitment of G protein-coupled receptor kinases (GRKs) controls signaling of the insulin-like growth factor 1 receptor.Role for engagement of β-arrestin2 by the transactivated EGFR in agonist-specific regulation of δ receptor activation of ERK1/2.β-Arrestin-biased agonism as the central mechanism of action for insulin-like growth factor 1 receptor-targeting antibodies in Ewing's sarcoma.TSH/IGF-1 Receptor Cross Talk in Graves' Ophthalmopathy Pathogenesis.Assessing the clinical utility of measuring Insulin-like Growth Factor Binding Proteins in tissues and sera of melanoma patientsMetformin Enhances the Therapy Effects of Anti-IGF-1R mAb Figitumumab to NSCLC.Upregulation of neurovascular communication through filamin abrogation promotes ectopic periventricular neurogenesis.The crosstalk between EGF, IGF, and Insulin cell signaling pathways--computational and experimental analysis.GAIP-interacting protein, C-terminus is involved in the induction of zinc-finger protein 143 in response to insulin-like growth factor-1 in colon cancer cellsBuilding the Case for Insulin-Like Growth Factor Receptor-I Involvement in Thyroid-Associated Ophthalmopathy.Role of β-arrestins and arrestin domain-containing proteins in G protein-coupled receptor trafficking.CD99 triggering induces methuosis of Ewing sarcoma cells through IGF-1R/RAS/Rac1 signaling.β-Arrestins 1 and 2 are critical regulators of inflammation.Expression of insulin-like growth factor-1 receptor in metastatic uveal melanoma and implications for potential autocrine and paracrine tumor cell growth.Targeting the IGF-1R: The Tale of the Tortoise and the Hare.
P2860
Q21131281-2CD972D0-D6E3-485F-8990-43845B7C3E51Q24306866-E20FAF39-BEE9-41D1-A870-488A85F7F826Q24306884-4350F084-CB9F-4A37-BE16-567B1AD21B4CQ27314982-E7344C64-35BE-4F34-AB5B-0ABA4BA4F618Q28268438-4513040A-18E2-4ACE-ACC2-56D0E79DEFCAQ28571736-4DB8BFB2-CCCB-406E-B6A6-9A5CF53589C0Q28572837-86DD7705-130A-462D-9B49-277308588D9CQ33280993-6DDB8DF6-3AAE-4143-91D3-82AFF6DAFA42Q33707151-5C7B113D-E86C-4B57-8EDF-A4DC5DD405CCQ34254212-C4107749-263C-4F08-B88D-47360706CA95Q34387886-26C85E6B-776B-4E5E-9F62-06E0F06DEBB2Q34429527-89ABBA30-2158-420A-A476-685B0EA2B6FBQ34431333-833143FE-C170-4196-A971-CE63E9B4A436Q34722516-C1A7ECB6-B4BF-4B46-9EC5-2D26346F1A51Q34801160-F321736C-8BB8-49C5-B867-1A192B8E660DQ34888305-DCB001B7-A67A-4031-86DE-71AA3F662B21Q34972287-C0683C93-5F09-4D22-927F-6E7AAA5025A4Q35037802-06C2C727-BBCC-46FB-916E-A2542382D430Q35131269-826DBEEB-A6B7-4B85-AAC6-B576835F5A24Q35201347-46F7D44C-979E-4AC3-B9D9-DEF365039B1BQ35424798-A16B9417-225A-4708-9C6E-1DAB56923B4EQ35565885-7241B1BB-2EFA-4616-A36D-82663A2DEA6BQ35609910-855A4A83-1729-45FF-9CE6-81069C60CE01Q35719489-686883FE-23AF-4886-9A55-7BCA234C002DQ35921791-BC17A9E4-31D3-47F3-BFB5-E4CEB6C40D93Q35935789-9617950C-B0F1-4976-B294-D2D422CB95A2Q36211185-9D10BF67-80AB-4E21-9E01-B90A72635C7AQ36483910-12538B6D-A1AA-44BA-B77E-48E10F5D183BQ36965291-AA1ED0CF-814A-43C0-9956-23A70D69E16EQ37064715-740C62B7-3F6A-4913-924D-C7999E65FFC2Q37151297-E7B927F8-EFE4-4677-BAB3-2BB4721ADABEQ37309763-1E180133-5330-4D41-A1B2-F3661F6019F7Q37362403-D80C431E-249E-486E-8652-DD0F7E2FC0B3Q37461421-8EAE582B-3595-41AA-83B9-AF52400EE22FQ37550127-203D210A-1CF8-4E56-9A35-ABF36E9FA4FEQ37676928-73DAD486-14CA-411D-849E-92EB84AABDB9Q37694869-AD722CE7-2A70-4836-A0AB-CFAA235D7677Q38136811-AC0584ED-61AD-4362-9796-52627444D5E3Q38393712-30B3ACAC-70FA-4116-827E-12F6EE3C34A8Q38474624-4E1802A9-B2FB-4829-9B30-D44DCBDED201
P2860
Beta-arrestin and Mdm2 mediate IGF-1 receptor-stimulated ERK activation and cell cycle progression.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Beta-arrestin and Mdm2 mediate ...... on and cell cycle progression.
@en
type
label
Beta-arrestin and Mdm2 mediate ...... on and cell cycle progression.
@en
prefLabel
Beta-arrestin and Mdm2 mediate ...... on and cell cycle progression.
@en
P2093
P2860
P356
P1476
Beta-arrestin and Mdm2 mediate ...... on and cell cycle progression.
@en
P2093
Ada Girnita
Bita Sehat
Daiana Vasilcanu
Leonard Girnita
Olle Larsson
Radu Vasilcanu
Robert J Lefkowitz
Sudha K Shenoy
P2860
P304
11329-11338
P356
10.1074/JBC.M611526200
P407
P577
2007-02-15T00:00:00Z