Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin.
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Identification of sequences common to more than one therapeutic target to treat complex diseases: simulating the high variance in sequence interactivity evolved to modulate robust phenotypesThe critical role of the central nervous system (pro)renin receptor in regulating systemic blood pressureReview article: the pathophysiological roles of the renin-angiotensin system in the gastrointestinal tractRoles of the (pro)renin receptor in the kidneyPhysiology of kidney reninCharacterization of a functional (pro)renin receptor in rat brain neuronsTargeted deletion of murine CEACAM 1 activates PI3K-Akt signaling and contributes to the expression of (Pro)renin receptor via CREB family and NF-κB transcription factors.Renal (pro)renin receptor contributes to development of diabetic kidney disease through transforming growth factor-β1-connective tissue growth factor signalling cascade.Regulation of (pro)renin receptor expression by glucose-induced mitogen-activated protein kinase, nuclear factor-kappaB, and activator protein-1 signaling pathways.(Pro)renin receptor contributes to diabetic nephropathy by enhancing renal inflammation.Glucose promotes the production of interleukine-1beta and cyclooxygenase-2 in mesangial cells via enhanced (Pro)renin receptor expressionProrenin and (pro)renin receptor: a review of available data from in vitro studies and experimental models in rodents.(Pro)renin receptor promotes choroidal neovascularization by activating its signal transduction and tissue renin-angiotensin system.eNOS knockout mice with advanced diabetic nephropathy have less benefit from renin-angiotensin blockade than from aldosterone receptor antagonists.A current view of brain renin-angiotensin system: Is the (pro)renin receptor the missing link?A Novel Single-Strand RNAi Therapeutic Agent Targeting the (Pro)renin Receptor Suppresses Ocular Inflammation.Comparative effect of direct renin inhibition and AT1R blockade on glomerular filtration barrier injury in the transgenic Ren2 ratAddressing the theoretical and clinical advantages of combination therapy with inhibitors of the renin-angiotensin-aldosterone system: antihypertensive effects and benefits beyond BP control.Expression of ACE and ACE2 in patients with hypertensive nephrosclerosis.Purification of functional baculovirus particles from silkworm larval hemolymph and their use as nanoparticles for the detection of human prorenin receptor (PRR) binding.Renin, (pro)renin and receptor: an update.Regression of superficial glomerular podocyte injury in type 2 diabetic rats with overt albuminuria: effect of angiotensin II blockadeDirect pro-inflammatory effects of prorenin on microglia.Renin and cardiovascular disease: Worn-out path, or new direction.The role of individual domains and the significance of shedding of ATP6AP2/(pro)renin receptor in vacuolar H(+)-ATPase biogenesis.New insights and perspectives on intrarenal renin-angiotensin system: focus on intracrine/intracellular angiotensin IICombined renin inhibition/(pro)renin receptor blockade in diabetic retinopathy--a study in transgenic (mREN2)27 rats.High salt intake damages the heart through activation of cardiac (pro) renin receptors even at an early stage of hypertension.Combining angiotensin II blockade and renin receptor inhibition results in enhanced antifibrotic effect in experimental nephritis.Role of non-classical renin-angiotensin system axis in renal fibrosis.Serum prorenin levels and diabetic retinopathy in type 2 diabetes: new method to measure serum level of prorenin using antibody activating direct kinetic assayAngiotensin II increases the expression of (pro)renin receptor during low-salt conditions.Renin and the (pro)renin receptor in the renal collecting duct: Role in the pathogenesis of hypertension.Prorenin receptor is essential for podocyte autophagy and survival.Prorenin receptor is essential for normal podocyte structure and functionAging, Angiotensin system and dopaminergic degeneration in the substantia nigra.Roles of collecting duct renin and (pro)renin receptor in hypertension: mini reviewBrain-targeted (pro)renin receptor knockdown attenuates angiotensin II-dependent hypertensionLiver angiotensinogen is the primary source of renal angiotensin II.ANG II-independent prorenin/(pro)renin receptor signaling pathways in the central nervous system.
P2860
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P2860
Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Inhibition of diabetic nephrop ...... olytic activation of prorenin.
@en
type
label
Inhibition of diabetic nephrop ...... olytic activation of prorenin.
@en
prefLabel
Inhibition of diabetic nephrop ...... olytic activation of prorenin.
@en
P2093
P2860
P356
P1476
Inhibition of diabetic nephrop ...... olytic activation of prorenin.
@en
P2093
A H M Nurun Nabi
Akira Nishiyama
Atsuhiro Ichihara
Fumiaki Suzuki
Hirokazu Okada
M Nasir Uddin
Matsuhiko Hayashi
Tadashi Inagami
Takao Saruta
Tsutomu Nakagawa
P2860
P304
P356
10.1172/JCI21398
P407
P577
2004-10-01T00:00:00Z