Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin. - Wikidata - wikimedia - TriplyDB

Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin.

Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin.

http://www.wikidata.org/entity/Q40176844

about

Identification of sequences common to more than one therapeutic target to treat complex diseases: simulating the high variance in sequence interactivity evolved to modulate robust phenotypes The critical role of the central nervous system (pro)renin receptor in regulating systemic blood pressure Review article: the pathophysiological roles of the renin-angiotensin system in the gastrointestinal tract Roles of the (pro)renin receptor in the kidney Physiology of kidney renin Characterization of a functional (pro)renin receptor in rat brain neurons Targeted deletion of murine CEACAM 1 activates PI3K-Akt signaling and contributes to the expression of (Pro)renin receptor via CREB family and NF-κB transcription factors.Renal (pro)renin receptor contributes to development of diabetic kidney disease through transforming growth factor-β1-connective tissue growth factor signalling cascade.Regulation of (pro)renin receptor expression by glucose-induced mitogen-activated protein kinase, nuclear factor-kappaB, and activator protein-1 signaling pathways.(Pro)renin receptor contributes to diabetic nephropathy by enhancing renal inflammation.Glucose promotes the production of interleukine-1beta and cyclooxygenase-2 in mesangial cells via enhanced (Pro)renin receptor expression Prorenin and (pro)renin receptor: a review of available data from in vitro studies and experimental models in rodents.(Pro)renin receptor promotes choroidal neovascularization by activating its signal transduction and tissue renin-angiotensin system.eNOS knockout mice with advanced diabetic nephropathy have less benefit from renin-angiotensin blockade than from aldosterone receptor antagonists.A current view of brain renin-angiotensin system: Is the (pro)renin receptor the missing link?A Novel Single-Strand RNAi Therapeutic Agent Targeting the (Pro)renin Receptor Suppresses Ocular Inflammation.Comparative effect of direct renin inhibition and AT1R blockade on glomerular filtration barrier injury in the transgenic Ren2 rat Addressing the theoretical and clinical advantages of combination therapy with inhibitors of the renin-angiotensin-aldosterone system: antihypertensive effects and benefits beyond BP control.Expression of ACE and ACE2 in patients with hypertensive nephrosclerosis.Purification of functional baculovirus particles from silkworm larval hemolymph and their use as nanoparticles for the detection of human prorenin receptor (PRR) binding.Renin, (pro)renin and receptor: an update.Regression of superficial glomerular podocyte injury in type 2 diabetic rats with overt albuminuria: effect of angiotensin II blockade Direct pro-inflammatory effects of prorenin on microglia.Renin and cardiovascular disease: Worn-out path, or new direction.The role of individual domains and the significance of shedding of ATP6AP2/(pro)renin receptor in vacuolar H(+)-ATPase biogenesis.New insights and perspectives on intrarenal renin-angiotensin system: focus on intracrine/intracellular angiotensin II Combined renin inhibition/(pro)renin receptor blockade in diabetic retinopathy--a study in transgenic (mREN2)27 rats.High salt intake damages the heart through activation of cardiac (pro) renin receptors even at an early stage of hypertension.Combining angiotensin II blockade and renin receptor inhibition results in enhanced antifibrotic effect in experimental nephritis.Role of non-classical renin-angiotensin system axis in renal fibrosis.Serum prorenin levels and diabetic retinopathy in type 2 diabetes: new method to measure serum level of prorenin using antibody activating direct kinetic assay Angiotensin II increases the expression of (pro)renin receptor during low-salt conditions.Renin and the (pro)renin receptor in the renal collecting duct: Role in the pathogenesis of hypertension.Prorenin receptor is essential for podocyte autophagy and survival.Prorenin receptor is essential for normal podocyte structure and function Aging, Angiotensin system and dopaminergic degeneration in the substantia nigra.Roles of collecting duct renin and (pro)renin receptor in hypertension: mini review Brain-targeted (pro)renin receptor knockdown attenuates angiotensin II-dependent hypertension Liver angiotensinogen is the primary source of renal angiotensin II.ANG II-independent prorenin/(pro)renin receptor signaling pathways in the central nervous system.

P2860

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P2860

Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin.

http://www.wikidata.org/entity/Q40176844

description

2004 nî lūn-bûn

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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2004年论文

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2004年论文

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name

Inhibition of diabetic nephrop ...... olytic activation of prorenin.

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type

label

Inhibition of diabetic nephrop ...... olytic activation of prorenin.

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prefLabel

Inhibition of diabetic nephrop ...... olytic activation of prorenin.

@en

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P1433

Journal of Clinical Investigation

P1476

Inhibition of diabetic nephrop ...... olytic activation of prorenin.

@en

P2093

A H M Nurun Nabi

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Akira Nishiyama

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Atsuhiro Ichihara

http://www.w3.org/2001/XMLSchema#string

Fumiaki Suzuki

http://www.w3.org/2001/XMLSchema#string

Hirokazu Okada

http://www.w3.org/2001/XMLSchema#string

M Nasir Uddin

http://www.w3.org/2001/XMLSchema#string

Matsuhiko Hayashi

http://www.w3.org/2001/XMLSchema#string

Tadashi Inagami

http://www.w3.org/2001/XMLSchema#string

Takao Saruta

http://www.w3.org/2001/XMLSchema#string

Tsutomu Nakagawa

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P2860

Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin

Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes

Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy

Renin and angiotensinogen expression during the evolution of diabetes.

Molecular cloning and identification of N-acyl-D-glucosamine 2-epimerase from porcine kidney as a renin-binding protein.

Thyroid hormone stimulates renin synthesis in rats without involving the sympathetic nervous system.

Vascular damage without hypertension in transgenic rats expressing prorenin exclusively in the liver.

Isoform switching of type IV collagen is developmentally arrested in X-linked Alport syndrome leading to increased susceptibility of renal basement membranes to endoproteolysis.

Phospholipase D contributes to transmural pressure control of prorenin processing in juxtaglomerular cell.

Renal interstitial fluid angiotensin I and angiotensin II concentrations during local angiotensin-converting enzyme inhibition.

P304

1128-1135

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scholarly article

P356

10.1172/JCI21398

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P433

8

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P478

114

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2004-10-01T00:00:00Z

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8226810

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15489960

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522242

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