Geldanamycin, an inhibitor of Hsp90, blocks cytoplasmic retention of progesterone receptors and glucocorticoid receptors via their respective ligand binding domains.
about
Development and validation of a high-content screening assay to identify inhibitors of cytoplasmic dynein-mediated transport of glucocorticoid receptor to the nucleus.The progesterone receptor hinge region regulates the kinetics of transcriptional responses through acetylation, phosphorylation, and nuclear retention.A ligand-specific kinetic switch regulates glucocorticoid receptor trafficking and function.Optimizing the protein switch: altering nuclear import and export signals, and ligand binding domain.No direct nuclear effect of progesterone in the inner ear: other possible pathways.
P2860
Geldanamycin, an inhibitor of Hsp90, blocks cytoplasmic retention of progesterone receptors and glucocorticoid receptors via their respective ligand binding domains.
description
2006 nî lūn-bûn
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2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
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2006年论文
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2006年论文
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name
Geldanamycin, an inhibitor of ...... ective ligand binding domains.
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type
label
Geldanamycin, an inhibitor of ...... ective ligand binding domains.
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prefLabel
Geldanamycin, an inhibitor of ...... ective ligand binding domains.
@en
P2093
P2860
P356
P1433
P1476
Geldanamycin, an inhibitor of ...... ective ligand binding domains.
@en
P2093
Carol S Lim
Charu Kanwal
J Rian Davis
Mudit Kakar
P2860
P2888
P304
P356
10.1208/AAPSJ080481
P407
P577
2006-11-22T00:00:00Z
P5875
P6179
1034915195