Impact of HIV-1 Integrase L74F and V75I Mutations in a Clinical Isolate on Resistance to Second-Generation Integrase Strand Transfer Inhibitors.

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Antiviral Activity of Bictegravir and Cabotegravir Against Integrase Inhibitor Resistant SIVmac239 and HIV-1.Structural Implications of Genotypic Variations in HIV-1 Integrase From Diverse Subtypes

P2860

Q41935102-0B83A852-0CC5-4D45-BA9E-D1FB98B6E590 Q56926444-678501FB-D1D7-4CA6-B583-437604F04882

P2860

Impact of HIV-1 Integrase L74F and V75I Mutations in a Clinical Isolate on Resistance to Second-Generation Integrase Strand Transfer Inhibitors.

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http://www.wikidata.org/entity/Q40190127

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2017 nî lūn-bûn

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2017年の論文

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2017年論文

@yue

2017年論文

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2017年論文

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2017年論文

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2017年論文

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2017年论文

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2017年论文

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2017年论文

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name

Impact of HIV-1 Integrase L74F ...... se Strand Transfer Inhibitors.

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type

Item

label

Impact of HIV-1 Integrase L74F ...... se Strand Transfer Inhibitors.

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Impact of HIV-1 Integrase L74F ...... se Strand Transfer Inhibitors.

@en

P1476

Impact of HIV-1 Integrase L74F ...... se Strand Transfer Inhibitors.

@en

P2093

Atsuko Hachiya

http://www.w3.org/2001/XMLSchema#string

Junji Imamura

http://www.w3.org/2001/XMLSchema#string

Masakazu Matsuda

http://www.w3.org/2001/XMLSchema#string

Reiko Okazaki

http://www.w3.org/2001/XMLSchema#string

Stefan G Sarafianos

http://www.w3.org/2001/XMLSchema#string

Urara Shigemi

http://www.w3.org/2001/XMLSchema#string

Yoko Ido

http://www.w3.org/2001/XMLSchema#string

Yoshiyuki Yokomaku

http://www.w3.org/2001/XMLSchema#string

P2860

HIV-1 integrase inhibitor resistance and its clinical implications

Broad antiretroviral activity and resistance profile of the novel human immunodeficiency virus integrase inhibitor elvitegravir (JTK-303/GS-9137)

Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance.

Structural and Functional Analyses of the Second-Generation Integrase Strand Transfer Inhibitor Dolutegravir (S/GSK1349572)

Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells

Dolutegravir interactions with HIV-1 integrase-DNA: structural rationale for drug resistance and dissociation kinetics

Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome

Primary mutations selected in vitro with raltegravir confer large fold changes in susceptibility to first-generation integrase inhibitors, but minor fold changes to inhibitors with second-generation resistance profiles.

Dolutegravir efficacy at 48 weeks in key subgroups of treatment-naive HIV-infected individuals in three randomized trials.

Substitutions at amino acid positions 143, 148, and 155 of HIV-1 integrase define distinct genetic barriers to raltegravir resistance in vivo.

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scholarly article

case report

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10.1128/AAC.00315-17

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English

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http://www.w3.org/2001/XMLSchema#string

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Karen A. Kirby

Yasumasa Iwatani

P577

2017-05-22T00:00:00Z

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P698

28533248

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P932

5527620

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Impact of HIV-1 Integrase L74F and V75I Mutations in a Clinical Isolate on Resistance to Second-Generation Integrase Strand Transfer Inhibitors.

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P2860

P2860

Impact of HIV-1 Integrase L74F and V75I Mutations in a Clinical Isolate on Resistance to Second-Generation Integrase Strand Transfer Inhibitors.

description

name

type

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P1433

P1476

P2093

P2860

P31

P356

P407

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P31

P356

P407

P433

P478

P50

P577

P698

P932