Multiple amino acid substitutions in hemagglutinin are necessary for wild-type measles virus to acquire the ability to use receptor CD46 efficiently.
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Crystal structure of measles virus hemagglutinin provides insight into effective vaccinesStructure of the measles virus hemagglutinin bound to the CD46 receptorPerspective on Global Measles Epidemiology and Control and the Role of Novel Vaccination StrategiesFunctional and structural characterization of neutralizing epitopes of measles virus hemagglutinin protein.Tumor cell marker PVRL4 (nectin 4) is an epithelial cell receptor for measles virusWild-type measles virus with the hemagglutinin protein of the edmonston vaccine strain retains wild-type tropism in macaquesLentiviral vectors displaying modified measles virus gp overcome pre-existing immunity in in vivo-like transduction of human T and B cells.A human lung carcinoma cell line supports efficient measles virus growth and syncytium formation via a SLAM- and CD46-independent mechanism.Paramyxoviruses: different receptors - different mechanisms of fusion.Dimerization Efficiency of Canine Distemper Virus Matrix Protein Regulates Membrane-Budding Activity.Measles virus glycoprotein-pseudotyped lentiviral vector-mediated gene transfer into quiescent lymphocytes requires binding to both SLAM and CD46 entry receptors.Mutant fusion proteins with enhanced fusion activity promote measles virus spread in human neuronal cells and brains of suckling hamsters.Epithelial-mesenchymal transition abolishes the susceptibility of polarized epithelial cell lines to measles virusAnalysis of VSV pseudotype virus infection mediated by rubella virus envelope proteins.In vivo tropism of attenuated and pathogenic measles virus expressing green fluorescent protein in macaques.Measles virus mutants possessing the fusion protein with enhanced fusion activity spread effectively in neuronal cells, but not in other cells, without causing strong cytopathology.Altered interaction of the matrix protein with the cytoplasmic tail of hemagglutinin modulates measles virus growth by affecting virus assembly and cell-cell fusion.Measles viruses possessing the polymerase protein genes of the Edmonston vaccine strain exhibit attenuated gene expression and growth in cultured cells and SLAM knock-in mice.Previously unrecognized amino acid substitutions in the hemagglutinin and fusion proteins of measles virus modulate cell-cell fusion, hemadsorption, virus growth, and penetration rate.The measles virus hemagglutinin β-propeller head β4-β5 hydrophobic groove governs functional interactions with nectin-4 and CD46 but not those with the signaling lymphocytic activation molecule.Crystallization and preliminary crystallographic analysis of the measles virus hemagglutinin in complex with the CD46 receptor.Amino Acid substitutions in matrix, fusion and hemagglutinin proteins of wild measles virus for adaptation to vero cells.Isolation and complete nucleotide sequence of the measles virus IMB-1 strain in China.Measles Vaccine.Cell-to-cell measles virus spread between human neurons dependent on the hemagglutinin and the hyperfusogenic fusion protein.Measles virus envelope pseudotyped lentiviral vectors transduce quiescent human HSCs at an efficiency without precedent
P2860
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P2860
Multiple amino acid substitutions in hemagglutinin are necessary for wild-type measles virus to acquire the ability to use receptor CD46 efficiently.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Multiple amino acid substituti ...... use receptor CD46 efficiently.
@en
type
label
Multiple amino acid substituti ...... use receptor CD46 efficiently.
@en
prefLabel
Multiple amino acid substituti ...... use receptor CD46 efficiently.
@en
P2860
P50
P356
P1433
P1476
Multiple amino acid substituti ...... use receptor CD46 efficiently
@en
P2093
Fumio Seki
Maino Tahara
P2860
P304
P356
10.1128/JVI.02449-06
P407
P577
2006-12-20T00:00:00Z