Generation and characterization of a stable MK2-EGFP cell line and subsequent development of a high-content imaging assay on the Cellomics ArrayScan platform to screen for p38 mitogen-activated protein kinase inhibitors.
about
Automated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin α1-antitrypsin ZA p38 substrate-specific MK2-EGFP translocation assay for identification and validation of new p38 inhibitors in living cells: a comprising alternative for acquisition of cellular p38 inhibition dataAn ultra high-throughput, whole-animal screen for small molecule modulators of a specific genetic pathway in Caenorhabditis elegansHCS campaign to identify selective inhibitors of IL-6-induced STAT3 pathway activation in head and neck cancer cell linesHigh-content pSTAT3/1 imaging assays to screen for selective inhibitors of STAT3 pathway activation in head and neck cancer cell lines.Development and validation of a high-content screening assay to identify inhibitors of cytoplasmic dynein-mediated transport of glucocorticoid receptor to the nucleus.Quantifying myosin light chain phosphorylation in single adherent cells with automated fluorescence microscopyCharacterization and optimization of a novel protein-protein interaction biosensor high-content screening assay to identify disruptors of the interactions between p53 and hDM2.High-content positional biosensor screening assay for compounds to prevent or disrupt androgen receptor and transcriptional intermediary factor 2 protein-protein interactions.Using Caenorhabditis elegans to study serpinopathies.Characterization of Zinc Influx Transporters (ZIPs) in Pancreatic β Cells: ROLES IN REGULATING CYTOSOLIC ZINC HOMEOSTASIS AND INSULIN SECRETION.The Rhodococcus equi virulence protein VapA disrupts endolysosome function and stimulates lysosome biogenesis.Finerenone Impedes Aldosterone-dependent Nuclear Import of the Mineralocorticoid Receptor and Prevents Genomic Recruitment of Steroid Receptor Coactivator-1.An overview of cell phenotypes in HCS: limitations and advantages.High Content Imaging Assays for IL-6-Induced STAT3 Pathway Activation in Head and Neck Cancer Cell Lines.High Content Positional Biosensor Assay to Screen for Compounds that Prevent or Disrupt Androgen Receptor and Transcription Intermediary Factor 2 Protein-Protein Interactions.
P2860
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P2860
Generation and characterization of a stable MK2-EGFP cell line and subsequent development of a high-content imaging assay on the Cellomics ArrayScan platform to screen for p38 mitogen-activated protein kinase inhibitors.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Generation and characterizatio ...... ted protein kinase inhibitors.
@en
type
label
Generation and characterizatio ...... ted protein kinase inhibitors.
@en
prefLabel
Generation and characterizatio ...... ted protein kinase inhibitors.
@en
P2093
P1476
Generation and characterizatio ...... ted protein kinase inhibitors.
@en
P2093
Carmen Laethem
Debra Nickischer
Oscar J Trask
Patricia A Johnston
Paul A Johnston
Ramani Kandasamy
Rhonda Gates Williams
P304
P356
10.1016/S0076-6879(06)14021-5
P407
P577
2006-01-01T00:00:00Z