Overexpression of the NOTCH1 intracellular domain inhibits cell proliferation and alters the neuroendocrine phenotype of medullary thyroid cancer cells.
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Thrombospondin 2 potentiates notch3/jagged1 signalingNotch Signaling in Neuroendocrine TumorsTargeting the Notch signaling pathway in cancer therapeuticsNotch pathway activation is essential for maintenance of stem-like cells in early tongue cancerHes1 is required for appropriate morphogenesis and differentiation during mouse thyroid gland developmentMedullary thyroid carcinoma: targeted therapies and future directionsSpecific glycogen synthase kinase-3 inhibition reduces neuroendocrine markers and suppresses neuroblastoma cell growthNotch in the development of thyroid C-cells and the treatment of medullary thyroid cancer.Inhibition of growth in medullary thyroid cancer cells with histone deacetylase inhibitors and lithium chloride.Focal adhesion kinase, a downstream mediator of Raf-1 signaling, suppresses cellular adhesion, migration, and neuroendocrine markers in BON carcinoid cellsAscl1/Mash1 is a novel target of Gli2 during Gli2-induced neurogenesis in P19 EC cells.Azacytidine induces cell cycle arrest and suppression of neuroendocrine markers in carcinoids.Loss of Notch1-dependent p21(Waf1/Cip1) expression influences the Notch1 outcome in tumorigenesis.Valproic acid activates Notch1 signaling and induces apoptosis in medullary thyroid cancer cellsInhibition of phosphatidylinositol 3-kinase/Akt signaling suppresses tumor cell proliferation and neuroendocrine marker expression in GI carcinoid tumorsCo-delivery of doxorubicin and siRNA using octreotide-conjugated gold nanorods for targeted neuroendocrine cancer therapy.Signaling mechanisms in neuroendocrine tumors as targets for therapy.Novel approaches in anaplastic thyroid cancer therapyXanthohumol inhibits the neuroendocrine transcription factor achaete-scute complex-like 1, suppresses proliferation, and induces phosphorylated ERK1/2 in medullary thyroid cancer.Thiocoraline activates the Notch pathway in carcinoids and reduces tumor progression in vivoIdentification and validation of Notch pathway activating compounds through a novel high-throughput screening method.A pilot phase II study of valproic acid for treatment of low-grade neuroendocrine carcinoma.Gene expression profile analyze the molecular mechanism of CXCR7 regulating papillary thyroid carcinoma growth and metastasisExpression of the active Notch1 decreases MTC tumor growth in vivo.Tumor-suppressor role of Notch3 in medullary thyroid carcinoma revealed by genetic and pharmacological induction.Notch1-mediated tumor suppression in cervical cancer with the involvement of SST signaling and its application in enhanced SSTR-targeted therapeutics.Silencing Notch-1 induces apoptosis and increases the chemosensitivity of prostate cancer cells to docetaxel through Bcl-2 and Bax.The North American Neuroendocrine Tumor Society consensus guideline for the diagnosis and management of neuroendocrine tumors: pheochromocytoma, paraganglioma, and medullary thyroid cancerChrysin suppresses achaete-scute complex-like 1 and alters the neuroendocrine phenotype of carcinoids.Potential Therapeutic Role of Z-Isochaihulactone in Lung Cancer through Induction of Apoptosis via Notch Signaling.Neuroendocrine tumor cell growth inhibition by ZM336372 through alterations in multiple signaling pathwaysChrysin activates Notch1 signaling and suppresses tumor growth of anaplastic thyroid carcinoma in vitro and in vivoTumor suppressor role of notch1 and raf-1 signaling in medullary thyroid cancer cells.Resveratrol induces differentiation markers expression in anaplastic thyroid carcinoma via activation of Notch1 signaling and suppresses cell growth.Histone deacetylase inhibitors upregulate Notch-1 and inhibit growth in pheochromocytoma cellsTautomycetin and tautomycin suppress the growth of medullary thyroid cancer cells via inhibition of glycogen synthase kinase-3beta.Notch1 mediates growth suppression of papillary and follicular thyroid cancer cells by histone deacetylase inhibitors.Current understanding and management of medullary thyroid cancer.Notch tumor suppressor functionSuberoyl bishydroxamic acid activates notch1 signaling and suppresses tumor progression in an animal model of medullary thyroid carcinoma.
P2860
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P2860
Overexpression of the NOTCH1 intracellular domain inhibits cell proliferation and alters the neuroendocrine phenotype of medullary thyroid cancer cells.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Overexpression of the NOTCH1 i ...... edullary thyroid cancer cells.
@en
type
label
Overexpression of the NOTCH1 i ...... edullary thyroid cancer cells.
@en
prefLabel
Overexpression of the NOTCH1 i ...... edullary thyroid cancer cells.
@en
P2093
P356
P1476
Overexpression of the NOTCH1 i ...... edullary thyroid cancer cells.
@en
P2093
Abram M Vaccaro
Herbert Chen
Mary A Ndiaye
Muthusamy Kunnimalaiyaan
P304
39819-39830
P356
10.1074/JBC.M603578200
P407
P577
2006-11-07T00:00:00Z