Resistance to alkyl-lysophospholipid-induced apoptosis due to downregulated sphingomyelin synthase 1 expression with consequent sphingomyelin- and cholesterol-deficiency in lipid rafts.
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Inhibition of sphingomyelin synthase (SMS) affects intracellular sphingomyelin accumulation and plasma membrane lipid organizationRoles of bioactive sphingolipids in cancer biology and therapeuticsSphingomyelin synthase 1 suppresses ceramide production and apoptosis post-photodamageAll members in the sphingomyelin synthase gene family have ceramide phosphoethanolamine synthase activityRole of sphingomyelin synthase in controlling the antimicrobial activity of neutrophils against Cryptococcus neoformansMacrophage sphingomyelin synthase 2 deficiency decreases atherosclerosis in miceCeramide mediates nanovesicle shedding and cell death in response to phosphatidylinositol ether lipid analogs and perifosine.Selective reduction in the sphingomyelin content of atherogenic lipoproteins inhibits their retention in murine aortas and the subsequent development of atherosclerosis.Pharmacologic inhibition of sphingomyelin synthase (SMS) activity reduces apolipoprotein-B secretion from hepatocytes and attenuates endotoxin-mediated macrophage inflammation.Sphingomyelin synthases regulate protein trafficking and secretionReducing plasma membrane sphingomyelin increases insulin sensitivity.Cog2 null mutant CHO cells show defective sphingomyelin synthesis.Intracellular lipid flux and membrane microdomains as organizing principles in inflammatory cell signalingSphingomyelin and sphingomyelin synthase (SMS) in the malignant transformation of glioma cells and in 2-hydroxyoleic acid therapy.Sphingomyelin synthase 2 (SMS2) deficiency attenuates LPS-induced lung injuryImpact of sphingomyelin synthase 1 deficiency on sphingolipid metabolism and atherosclerosis in mice.Suppression of sphingomyelin synthase 1 by small interference RNA is associated with enhanced ceramide production and apoptosis after photodamageSphingomyelin synthase 2 is one of the determinants for plasma and liver sphingomyelin levels in miceSphingomyelin synthases regulate production of diacylglycerol at the Golgi.Glycosidated phospholipids: uncoupling of signalling pathways at the plasma membrane.Organization of the synthesis of glycolipid oligosaccharides in the Golgi complex.Phosphoinositide phosphatase SHIP-1 regulates apoptosis induced by edelfosine, Fas ligation and DNA damage in mouse lymphoma cells.Fas/CD95 down-regulation in lymphoma cells through acquired alkyllysophospholipid resistance: partial role of associated sphingomyelin deficiency.Pharmacokinetics and biodistribution of Erufosine in nude mice--implications for combination with radiotherapy.Mechanisms involved in cellular ceramide homeostasisCaspase-mediated inhibition of sphingomyelin synthesis is involved in FasL-triggered cell death.Variations in the effects on synthesis of amyloid beta protein in modulated autophagic conditions.Molecular cloning, sequence characterization, and tissue expression analysis of chicken sphingomyelin synthase 1 (SMS1).Pharmacological Activation of Peroxisome Proliferator-Activated Receptor {Delta} Increases Sphingomyelin Synthase Activity in THP-1 Macrophage-Derived Foam Cell.Bcr-Abl regulation of sphingomyelin synthase 1 reveals a novel oncogenic-driven mechanism of protein up-regulation.Reorganization of prion protein membrane environment during low potassium-induced apoptosis in primary rat cerebellar neurons
P2860
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P2860
Resistance to alkyl-lysophospholipid-induced apoptosis due to downregulated sphingomyelin synthase 1 expression with consequent sphingomyelin- and cholesterol-deficiency in lipid rafts.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Resistance to alkyl-lysophosph ...... rol-deficiency in lipid rafts.
@en
type
label
Resistance to alkyl-lysophosph ...... rol-deficiency in lipid rafts.
@en
prefLabel
Resistance to alkyl-lysophosph ...... rol-deficiency in lipid rafts.
@en
P2093
P2860
P356
P1433
P1476
Resistance to alkyl-lysophosph ...... rol-deficiency in lipid rafts.
@en
P2093
Arnold H Van der Luit
Jeffrey B Klarenbeek
Marcel Verheij
Marianne Budde
Shuraila Zerp
Wendy Caan
Wim J Van Blitterswijk
P2860
P304
P356
10.1042/BJ20061178
P407
P577
2007-01-01T00:00:00Z