Muscle-derived but not centrally derived transgene GDNF is neuroprotective in G93A-SOD1 mouse model of ALS.
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Mechanisms of Muscle Denervation in Aging: Insights from a Mouse Model of Amyotrophic Lateral SclerosisThe complex molecular biology of amyotrophic lateral sclerosis (ALS)ALS as a distal axonopathy: molecular mechanisms affecting neuromuscular junction stability in the presymptomatic stages of the diseaseGDNF secreting human neural progenitor cells protect dying motor neurons, but not their projection to muscle, in a rat model of familial ALS.Systemic injection of AAV9-GDNF provides modest functional improvements in the SOD1G93A ALS rat but has adverse side effects.Safety of repeated transplantations of neurotrophic factors-secreting human mesenchymal stromal stem cellsThe differential effects of pathway- versus target-derived glial cell line-derived neurotrophic factor on peripheral nerve regeneration.Neurotrophic growth factors for the treatment of amyotrophic lateral sclerosis: where do we stand?Neuroprotection for amyotrophic lateral sclerosis: role of stem cells, growth factors, and gene therapy.Dihydrotestosterone ameliorates degeneration in muscle, axons and motoneurons and improves motor function in amyotrophic lateral sclerosis model mice.Analysis of neurotrophic factors in limb and extraocular muscles of mouse model of amyotrophic lateral sclerosisTherapeutic potential of mesenchymal stromal cells and MSC conditioned medium in Amyotrophic Lateral Sclerosis (ALS)--in vitro evidence from primary motor neuron cultures, NSC-34 cells, astrocytes and microglia.Enhanced neuronal Met signalling levels in ALS mice delay disease onset.Motor neuron trophic factors: therapeutic use in ALS?Tetanus toxin C-fragment: the courier and the cure?Impaired motoneuronal retrograde transport in two models of SBMA implicates two sites of androgen action.Reactive oxygen species in skeletal muscle signaling.The lack of effect of specific overexpression of IGF-1 in the central nervous system or skeletal muscle on pathophysiology in the G93A SOD-1 mouse model of ALS.Recent advances in amyotrophic lateral sclerosis research: perspectives for personalized clinical applicationMicroNeurotrophins Improve Survival in Motor Neuron-Astrocyte Co-Cultures but Do Not Improve Disease Phenotypes in a Mutant SOD1 Mouse Model of Amyotrophic Lateral Sclerosis.Early vulnerability to ischemia/reperfusion injury in motor terminals innervating fast muscles of SOD1-G93A mice.Characterization of the Contribution of Genetic Background and Gender to Disease Progression in the SOD1 G93A Mouse Model of Amyotrophic Lateral Sclerosis: A Meta-Analysis.Short-term exercise increases GDNF protein levels in the spinal cord of young and old ratsSkeletal muscle in motor neuron diseases: therapeutic target and delivery route for potential treatments.Synergistic effects of GDNF and VEGF on lifespan and disease progression in a familial ALS rat modelRetrograde axonal transport and motor neuron disease.Direct muscle delivery of GDNF with human mesenchymal stem cells improves motor neuron survival and function in a rat model of familial ALSTransgenic models of nerve repair and nerve regeneration.Stem cells: comprehensive treatments for amyotrophic lateral sclerosis in conjunction with growth factor delivery.Neuromuscular Junction Impairment in Amyotrophic Lateral Sclerosis: Reassessing the Role of Acetylcholinesterase.Astrocytes and microglia: responses to neuropathological conditions.The Role of Skeletal Muscle in Amyotrophic Lateral Sclerosis.Secreted trophic factors of Human umbilical cord stromal cells induce differentiation and neurite extension through PI3K and independent of cAMP pathway.Calcitonin gene-related peptide regulation of glial cell-line derived neurotrophic factor in differentiated rat myotubes.Bone marrow transplantation in hindlimb muscles of motoneuron degenerative mice reduces neuronal death and improves motor function.Therapeutic effect of myogenic cells modified to express neurotrophic factors in a rat model of sciatic nerve injury.Strategy for treating motor neuron diseases using a fusion protein of botulinum toxin binding domain and streptavidin for viral vector access: work in progress.Neuromuscular junction protection for the potential treatment of amyotrophic lateral sclerosis.Presymptomatic biochemical changes in hindlimb muscle of G93A human Cu/Zn superoxide dismutase 1 transgenic mouse model of amyotrophic lateral sclerosisNeuromuscular Junction Dismantling in Amyotrophic Lateral Sclerosis.
P2860
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P2860
Muscle-derived but not centrally derived transgene GDNF is neuroprotective in G93A-SOD1 mouse model of ALS.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Muscle-derived but not central ...... G93A-SOD1 mouse model of ALS.
@en
type
label
Muscle-derived but not central ...... G93A-SOD1 mouse model of ALS.
@en
prefLabel
Muscle-derived but not central ...... G93A-SOD1 mouse model of ALS.
@en
P2093
P1476
Muscle-derived but not central ...... G93A-SOD1 mouse model of ALS.
@en
P2093
Alexander Parsadanian
Dan Hunter
Danielle Brakefield
Terence M Myckatyn
Yanchun Pan
P304
P356
10.1016/J.EXPNEUROL.2006.08.028
P407
P577
2006-10-10T00:00:00Z