Trim5alpha accelerates degradation of cytosolic capsid associated with productive HIV-1 entry.
about
Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradationCell-to-cell transmission of retroviruses: Innate immunity and interferon-induced restriction factorsFates of retroviral core components during unrestricted and TRIM5-restricted infectionProteasomal degradation of TRIM5alpha during retrovirus restrictionStabilized human TRIM5α protects human T cells from HIV-1 infection.Role of human immunodeficiency virus type 1 integrase in uncoating of the viral core.Phosphorylation of the HIV-1 capsid by MELK triggers uncoating to promote viral cDNA synthesis.Cyclophilin A restricts influenza A virus replication through degradation of the M1 protein.African green monkey TRIM5α restriction in simian immunodeficiency virus-specific rhesus macaque effector CD4 T cells enhances their survival and antiviral function.The human TRIM5alpha restriction factor mediates accelerated uncoating of the N-tropic murine leukemia virus capsid.Modulation of retroviral restriction and proteasome inhibitor-resistant turnover by changes in the TRIM5alpha B-box 2 domain.Visualization of a proteasome-independent intermediate during restriction of HIV-1 by rhesus TRIM5alpha.Antiretroviral activity of ancestral TRIM5alpha.Cellular restriction of retrovirus particle-mediated mRNA transfer.Independent genesis of chimeric TRIM5-cyclophilin proteins in two primate species.Host restriction factors blocking retroviral replicationCapsid proteins from human immunodeficiency virus type 1 and simian immunodeficiency virus SIVmac can coassemble into mature cores of infectious viruses.The control of viral infection by tripartite motif proteins and cyclophilin A.Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21.Mode of transmission affects the sensitivity of human immunodeficiency virus type 1 to restriction by rhesus TRIM5alpha.Correlation of naturally occurring HIV-1 resistance to DEB025 with capsid amino acid polymorphismsViral attachment induces rapid recruitment of an innate immune sensor (TRIM5α) to the plasma membrane.Proteasome-independent degradation of HIV-1 in naturally non-permissive human placental trophoblast cellsHIV-1 uncoating: connection to nuclear entry and regulation by host proteins.Recent insights into the mechanism and consequences of TRIM5α retroviral restriction.Both TRIM5alpha and TRIMCyp have only weak antiviral activity in canine D17 cells.Rhesus monkey TRIM5α represses HIV-1 LTR promoter activity by negatively regulating TAK1/TAB1/TAB2/TAB3-complex-mediated NF-κB activation.TRIM5 gene polymorphisms in HIV-1-infected patients and healthy controls from Northeastern Brazil.
P2860
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P2860
Trim5alpha accelerates degradation of cytosolic capsid associated with productive HIV-1 entry.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Trim5alpha accelerates degrada ...... d with productive HIV-1 entry.
@en
type
label
Trim5alpha accelerates degrada ...... d with productive HIV-1 entry.
@en
prefLabel
Trim5alpha accelerates degrada ...... d with productive HIV-1 entry.
@en
P2093
P2860
P356
P1476
Trim5alpha accelerates degrada ...... d with productive HIV-1 entry.
@en
P2093
Dennis Sheeter
Michael D Bobardt
Philippe A Gallay
Udayan Chatterji
P2860
P304
37025-37033
P356
10.1074/JBC.M606066200
P407
P577
2006-10-06T00:00:00Z