LY294,002, a specific inhibitor of PI3K/Akt kinase pathway, antagonizes P-glycoprotein-mediated multidrug resistance.
about
13-methyltetradecanoic acid exhibits anti-tumor activity on T-cell lymphomas in vitro and in vivo by down-regulating p-AKT and activating caspase-3LAPTM4B: a novel cancer-associated gene motivates multidrug resistance through efflux and activating PI3K/AKT signalingReversal effect of ST6GAL 1 on multidrug resistance in human leukemia by regulating the PI3K/Akt pathway and the expression of P-gp and MRP1FUT family mediates the multidrug resistance of human hepatocellular carcinoma via the PI3K/Akt signaling pathway.Increased p38-MAPK is responsible for chemotherapy resistance in human gastric cancer cells.ABC transporters in CSCs membranes as a novel target for treating tumor relapse.PIK3CA and PIK3CB expression and relationship with multidrug resistance in colorectal carcinoma.Biological profile of erucin: a new promising anticancer agent from cruciferous vegetables.Suppression of MAPK Signaling and Reversal of mTOR-Dependent MDR1-Associated Multidrug Resistance by 21α-Methylmelianodiol in Lung Cancer CellsPotentiation of anticancer drugs: effects of pentoxifylline on neoplastic cellsPI3K/Akt inhibition and down-regulation of BCRP re-sensitize MCF7 breast cancer cell line to mitoxantrone chemotherapy.Cytotoxicity of the Sesquiterpene Lactones Neoambrosin and Damsin from Ambrosia maritima Against Multidrug-Resistant Cancer CellsThe role of E3 ubiquitin ligase Cbl proteins in β-elemene reversing multi-drug resistance of human gastric adenocarcinoma cellsRedox regulation of multidrug resistance in cancer chemotherapy: molecular mechanisms and therapeutic opportunitiesDelineating the Role of βIV-Tubulins in Pancreatic Cancer: βIVb-Tubulin Inhibition Sensitizes Pancreatic Cancer Cells to Vinca Alkaloids.Musashi-1 regulates AKT-derived IL-6 autocrinal/paracrinal malignancy and chemoresistance in glioblastomaABC transporters as molecular effectors of pancreatic oncogenic pathways: the Hedgehog-GLI model.Tumour endothelial cells acquire drug resistance in a tumour microenvironment.ASIC1a mediates the drug resistance of human hepatocellular carcinoma via the Ca2+/PI3-kinase/AKT signaling pathway.PIK3CA and PIK3CB silencing by RNAi reverse MDR and inhibit tumorigenic properties in human colorectal carcinoma.α-2,8-Sialyltransferase Is Involved in the Development of Multidrug Resistance via PI3K/Akt Pathway in Human Chronic Myeloid Leukemia.CD133 and DNA-PK regulate MDR1 via the PI3K- or Akt-NF-κB pathway in multidrug-resistant glioblastoma cells in vitro.Reversal of P-glycoprotein-mediated multidrug resistance of human hepatic cancer cells by Astragaloside II.Chemoresistance of Lung and Breast Cancer Cells Growing Under Prolonged Periods of Serum Starvation.Constitutively active Akt contributes to vincristine resistance in human retinoblastoma cells.Versatile inhibitory effects of the flavonoid-derived PI3K/Akt inhibitor, LY294002, on ATP-binding cassette transporters that characterize stem cells.Modification of sialylation is associated with multidrug resistance in human acute myeloid leukemia.Lysosome-associated protein transmembrane4β is involved in multidrug resistance processes of colorectal cancer.Inhibition of the PI3K/AKT Pathway Sensitizes Oral Squamous Cell Carcinoma Cells to Anthracycline-Based Chemotherapy In Vitro.Cholecalciferol-PEG Conjugate Based Nanomicelles of Doxorubicin for Treatment of Triple-Negative Breast Cancer.Kanglaite reverses multidrug resistance of HCC by inducing apoptosis and cell cycle arrest via PI3K/AKT pathway.
P2860
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P2860
LY294,002, a specific inhibitor of PI3K/Akt kinase pathway, antagonizes P-glycoprotein-mediated multidrug resistance.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
LY294,002, a specific inhibito ...... mediated multidrug resistance.
@en
type
label
LY294,002, a specific inhibito ...... mediated multidrug resistance.
@en
prefLabel
LY294,002, a specific inhibito ...... mediated multidrug resistance.
@en
P2093
P1476
LY294,002, a specific inhibito ...... mediated multidrug resistance.
@en
P2093
Albert Breier
Ján Sedlák
Miroslav Barancík
Vierka Bohácová
Zdenka Sulová
P304
P356
10.1016/J.EJPS.2006.08.006
P407
P577
2006-08-22T00:00:00Z