Space-filling models of kinase clefts and conformation changes.
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Glucokinase mutations associated with non-insulin-dependent (type 2) diabetes mellitus have decreased enzymatic activity: implications for structure/function relationships6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysisA database of macromolecular motionsThe high resolution crystal structure of yeast hexokinase PII with the correct primary sequence provides new insights into its mechanism of actionCrystal structure of the ADP-dependent glucokinase from Pyrococcus horikoshii at 2.0-Å resolution: A large conformational change in ADP-dependent glucokinaseAn autoinhibitory helix in the C-terminal region of phospholipase C-β mediates Gαq activationPurification and characterization of a novel ADP-dependent glucokinase from the hyperthermophilic archaeon Pyrococcus furiosusVisualizing lowly-populated regions of the free energy landscape of macromolecular complexes by paramagnetic relaxation enhancementBiochemical characterization of equine herpesvirus type 3-induced deoxythymidine kinase purified from lytically infected horse embryo dermal fibroblasts.Substrate-induced changes in protease active site conformation impact on subsequent reactions with substrates.Active site trapping of nucleotides by crosslinking two sulfhydryls in myosin subfragment 1.Induced fit in arginine kinase.Consensus topography in the ATP binding site of the simian virus 40 and polyomavirus large tumor antigens.Conformational change in substrate binding, catalysis and product release: an open and shut case?The conserved lysine of the catalytic domain of protein kinases is actively involved in the phosphotransfer reaction and not required for anchoring ATPMultiple phosphate positions in the catalytic site of glycogen phosphorylase: structure of the pyridoxal-5'-pyrophosphate coenzyme-substrate analog.Electron microscopy of glycogen degrading enzymes.Induced fit in guanidino kinases--comparison of substrate-free and transition state analog structures of arginine kinase.Computer simulation of the dynamics of hydrated protein crystals and its comparison with x-ray dataPurification and kinetic characterization of the mitogen-activated protein kinase phosphatase rVH6.Isolation of a glucan-binding domain of glucosyltransferase (1,6-alpha-glucan synthase) from Streptococcus sobrinusBinding energy, conformational change, and the mechanism of transmembrane solute movementsDomain motions in phosphoglycerate kinase: determination of interdomain distance distributions by site-specific labeling and time-resolved fluorescence energy transferLocating a nucleotide-binding site in the thymidine kinase of vaccinia virus and of herpes simplex virus by scoring triply aligned protein sequences.Dynamic filtering by two-dimensional 1H NMR with application to phage lambda repressor.The intracellular equilibrium thermodynamic and steady-state concentrations of metabolites.Human beta-cell glucokinase. Dual role of Ser-151 in catalysis and hexose affinity.An electrochemical interpretation of metabolism.Wheat phosphoglycerate kinase: evidence for recombination between the genes for the chloroplastic and cytosolic enzymes.Functional domains of yeast hexokinase 2.A ligand-induced conformational change in the Yersinia protein tyrosine phosphatase.Analysis of conformational motions and residue fluctuations for Escherichia coli ribose-binding protein revealed with elastic network models.Resonance energy transfer evidence for two attached states of the actomyosin complex.The interaction of yeast hexokinase with Procion Green H-4G.Mechanical deformation enhances catalytic activity of crystalline carboxypeptidase A.Protein clefts in molecular recognition and function.Crystal structure of bacterial inorganic polyphosphate/ATP-glucomannokinase. Insights into kinase evolution.Conformational changes: how small is big enough?Characteristics of rabbit muscle adenylate kinase inhibition by sulfur and recovery by dithiothreitol.Building blocks, hinge-bending motions and protein topology.
P2860
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P2860
Space-filling models of kinase clefts and conformation changes.
description
1979 nî lūn-bûn
@nan
1979年の論文
@ja
1979年論文
@yue
1979年論文
@zh-hant
1979年論文
@zh-hk
1979年論文
@zh-mo
1979年論文
@zh-tw
1979年论文
@wuu
1979年论文
@zh
1979年论文
@zh-cn
name
Space-filling models of kinase clefts and conformation changes.
@en
type
label
Space-filling models of kinase clefts and conformation changes.
@en
prefLabel
Space-filling models of kinase clefts and conformation changes.
@en
P2093
P356
P1433
P1476
Space-filling models of kinase clefts and conformation changes.
@en
P2093
P304
P356
10.1126/SCIENCE.220706
P407
P577
1979-04-01T00:00:00Z