Inhibition of the hyaluronan-CD44 interaction by merlin contributes to the tumor-suppressor activity of merlin.
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Interactions between Hyaluronan and Its Receptors (CD44, RHAMM) Regulate the Activities of Inflammation and CancerConcise Review: Emerging Role of CD44 in Cancer Stem Cells: A Promising Biomarker and Therapeutic TargetMerlin, a "magic" linker between extracellular cues and intracellular signaling pathways that regulate cell motility, proliferation, and survivalIn vitro and in vivo prostate cancer metastasis and chemoresistance can be modulated by expression of either CD44 or CD147Therapeutic potential of HSP90 inhibition for neurofibromatosis type 2.Molecular mechanisms promoting the pathogenesis of Schwann cell neoplasmsLoss of SOX10 function contributes to the phenotype of human Merlin-null schwannoma cells.Merlin knockdown in human Schwann cells: clues to vestibular schwannoma tumorigenesisStable alterations of CD44 isoform expression in prostate cancer cells decrease invasion and growth and alter ligand binding and chemosensitivity.CD44 attenuates activation of the hippo signaling pathway and is a prime therapeutic target for glioblastomaMerlin is a negative regulator of human melanoma growthLoss of tumor suppressor Merlin in advanced breast cancer is due to post-translational regulation.Dual role of CD44 isoforms in ampullary adenocarcinoma: CD44s predicts poor prognosis in early cancer and CD44ν is an indicator for recurrence in advanced cancer.Role of Merlin/NF2 inactivation in tumor biology.AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins, inhibits progression of human ovarian cancer.Merlin is a potent inhibitor of glioma growthFRMD6 inhibits human glioblastoma growth and progression by negatively regulating activity of receptor tyrosine kinases.Role of hyaluronan-mediated CD44 signaling in head and neck squamous cell carcinoma progression and chemoresistance.Inactivation of Merlin in malignant mesothelioma cells and the Hippo signaling cascade dysregulation.Merlin: the wizard requires protein stability to function as a tumor suppressor.Schwannomas and their pathogenesis.Tumor suppressor role of protein 4.1B/DAL-1.The Hippo pathway in chemotherapeutic drug resistance.Loss of tumor suppressor Merlin results in aberrant activation of Wnt/β-catenin signaling in cancerFunctional interdependence of NHE1 and merlin in human melanoma cells.Phenyl-methylene hydantoins alter CD44-specific ligand binding of benign and malignant prostate cells and suppress CD44 isoform expression.The neurofibromatosis 2 protein, merlin, regulates glial cell growth in an ErbB2- and Src-dependent mannerAngiopoietin-4 promotes glioblastoma progression by enhancing tumor cell viability and angiogenesis.Lack of neurofibromatosis type 2 gene promoter methylation in sporadic vestibular schwannomas.Protein kinase A-mediated phosphorylation of the NF2 tumor suppressor protein merlin at serine 10 affects the actin cytoskeleton.DNA copy gains of tumor-related genes in vestibular schwannoma.
P2860
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P2860
Inhibition of the hyaluronan-CD44 interaction by merlin contributes to the tumor-suppressor activity of merlin.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Inhibition of the hyaluronan-C ...... suppressor activity of merlin.
@en
type
label
Inhibition of the hyaluronan-C ...... suppressor activity of merlin.
@en
prefLabel
Inhibition of the hyaluronan-C ...... suppressor activity of merlin.
@en
P2093
P2860
P356
P1433
P1476
Inhibition of the hyaluronan-C ...... suppressor activity of merlin.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1209849
P407
P577
2006-09-04T00:00:00Z
P5875
P6179
1034283203