The EphB4 receptor-tyrosine kinase promotes the migration of melanoma cells through Rho-mediated actin cytoskeleton reorganization.
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Ephrin-B2 elicits differential growth cone collapse and axon retraction in retinal ganglion cells from distinct retinal regions.Variable combinations of specific ephrin ligand/Eph receptor pairs control embryonic tissue separationLithocholic acid is an Eph-ephrin ligand interfering with Eph-kinase activationPEGylation potentiates the effectiveness of an antagonistic peptide that targets the EphB4 receptor with nanomolar affinitySinusoidal ephrin receptor EPHB4 controls hematopoietic progenitor cell mobilization from bone marrow.Staurosporine augments EGF-mediated EMT in PMC42-LA cells through actin depolymerisation, focal contact size reduction and Snail1 induction - a model for cross-modulationSoluble EphB4 inhibition of PDGF-induced RPE migration in vitro.Eph receptors and ephrins in cancer: bidirectional signalling and beyond.Essential roles of EphB receptors and EphrinB ligands in endothelial cell function and angiogenesis.Converging evidence for efficacy from parallel EphB4-targeted approaches in ovarian carcinoma.EphB2 activation is required for ependymoma development as well as inhibits differentiation and promotes proliferation of the transformed cell.A disalicylic acid-furanyl derivative inhibits ephrin binding to a subset of Eph receptorsEphB4/ephrinB2 Contributes to Imatinib Resistance in Chronic Myeloid Leukemia Involved in Cytoskeletal Proteins.The EphA2 receptor and ephrinA1 ligand in solid tumors: function and therapeutic targeting.Membrane-mediated regulation of vascular identity.Predicting and preventing melanoma invasiveness: advances in clarifying E2F1 function.Eph-dependent cell-cell adhesion and segregation in development and cancer.The Eph/Ephrin family in cancer metastasis: communication at the service of invasion.Eph- and ephrin-dependent mechanisms in tumor and stem cell dynamics.The EphB4 receptor tyrosine kinase promotes lung cancer growth: a potential novel therapeutic target.EphB4 is overexpressed in gliomas and promotes the growth of glioma cells.Fluorine-18 radiolabeling and radiopharmacological characterization of a benzodioxolylpyrimidine-based radiotracer targeting the receptor tyrosine kinase EphB4.EphB4 is overexpressed in papillary thyroid carcinoma and promotes the migration of papillary thyroid cancer cells.Evidence for a dual function of EphB4 as tumor promoter and suppressor regulated by the absence or presence of the ephrin-B2 ligand.Recognition of CD146 as an ERM-binding protein offers novel mechanisms for melanoma cell migration.Clinical significance of EphA2 expression in squamous-cell carcinoma of the head and neck.Ephrin-independent regulation of cell substrate adhesion by the EphB4 receptor.EphrinA1 activates a Src/focal adhesion kinase-mediated motility response leading to rho-dependent actino/myosin contractility.A review on Eph/ephrin, angiogenesis and lymphangiogenesis in gastric, colorectal and pancreatic cancersDesign, synthesis and characterization of novel small molecular inhibitors of ephrin-B2 binding to EphB4.The EphB4 receptor promotes the growth of melanoma cells expressing the ephrin-B2 ligand.Expression of the EPHB4 receptor tyrosine kinase in head and neck and renal malignancies--implications for solid tumors and potential for therapeutic inhibition.lncRNA BC005927 upregulates EPHB4 and promotes gastric cancer metastasis under hypoxia.Increased EphB2 expression predicts cholangiocarcinoma metastasis.From Neural Crest Development to Cancer and Vice Versa: How p75 and (Pro)neurotrophins Could Act on Cell Migration and Invasion?
P2860
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P2860
The EphB4 receptor-tyrosine kinase promotes the migration of melanoma cells through Rho-mediated actin cytoskeleton reorganization.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
The EphB4 receptor-tyrosine ki ...... n cytoskeleton reorganization.
@en
type
label
The EphB4 receptor-tyrosine ki ...... n cytoskeleton reorganization.
@en
prefLabel
The EphB4 receptor-tyrosine ki ...... n cytoskeleton reorganization.
@en
P2093
P2860
P356
P1476
The EphB4 receptor-tyrosine ki ...... n cytoskeleton reorganization.
@en
P2093
Elena B Pasquale
Iryna M Ethell
Laurie B Owen
Nai-Ying Yang
P2860
P304
32574-32586
P356
10.1074/JBC.M604338200
P407
P577
2006-08-31T00:00:00Z